262444-42-8

Basic information

• Product Name: tert-butyl-2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-ioxaborolan-2-yl)phenylcarbamate
• Synonyms: tert-butyl-2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-ioxaborolan-2-yl)phenylcarbamate;4-(BOC-amino)-3-fluorophenylboronic acid,pinacol;N-Boc-4-amino-3-fluorophenylboronic Acid Pinacol Ester;N-Boc-4-amino-3-fluorophenylboronic acid pi;4-(BOC-amino)-3-fluorophenyl boronic acid, pinacol ester;t-Butyl 2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenylcarbamate;N-tert-butyl-N-[2-fluoro-4-(tetraMethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbaMate;tert-butyl N-[2-fluoro-4-(tetraMethyl-1,3,2- dioxaborolan-2-yl)phenyl]carbaMate
• CAS NO: 262444-42-8
• Molecular Formula: C₁₇H₂₅BFNO₄
• Molecular Weight: 337.197
• Mol File: 262444-42-8.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 376.622 °C at 760 mmHg
• Flash Point: 181.575 °C
• Appearance: /
• Density: 1.11
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.496
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 12.91±0.70(Predicted)
• CAS DataBase Reference: tert-butyl-2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-ioxaborolan-2-yl)phenylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl-2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-ioxaborolan-2-yl)phenylcarbamate(262444-42-8)
• EPA Substance Registry System: tert-butyl-2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-ioxaborolan-2-yl)phenylcarbamate(262444-42-8)

Safety Data

• Hazardous Substances Data: 262444-42-8(Hazardous Substances Data)

Usage

General Description

Tert-butyl-2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-ioxaborolan-2-yl)phenylcarbamate is a complex organic compound with the chemical formula C19H28BFNO3. It is a carbamate derivative with a tert-butyl group attached to a 2-fluoro-4-phenylcarbamate moiety, and a boron-containing oxaborolane group. tert-butyl-2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-ioxaborolan-2-yl)phenylcarbamate is commonly used in the pharmaceutical and agrochemical industries as a versatile building block for the synthesis of various biologically active compounds. Additionally, it has potential applications in medicinal chemistry and drug discovery research due to its unique structural properties and reactivity.

InChI:InChI=1/C17H25BFNO4/c1-15(2,3)22-14(21)20-13-9-8-11(10-12(13)19)18-23-16(4,5)17(6,7)24-18/h8-10H,1-7H3,(H,20,21)

Upstream product

• 367-24-8 4-bromo-2-fluoroaniline 
• 24424-99-5 di-tert-butyl dicarbonate 
• 209958-42-9 tert-butyl N-(4-bromo-2-fluorophenyl)carbamate 
• 76-09-5 2,3-dimethyl-2,3-butane diol 
• 218301-87-2 4-(tert-butoxycarbonylamino)-3-fluorophenylboronic acid 

Downstream Products

• 819058-34-9 2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline 
• 939967-96-1 tert-butyl {4-[4-amino-7-(morpholin-4-ylmethyl)pyrrolo[2,1-f][1,2,4]triazin-5-yl]-2-fluorophenyl}carbamate 
• 939807-38-2 ethyl 4-{4-[(tertbutoxycarbonylamino)]-3-fluorophenyl}-5-cyano-1-{[2-(trimethylsiIyl)ethoxy]methyl}-1H-pyrrole-3-carboxylate 
• 330793-36-7 ethyl 2-(4-amino-3-4-[(tert-butoxycarbonyl)amino]-3-fluorophenyl-1H-pyrazolo[3,4-d]pyrimidin-1-yl)acetate 

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