26281-43-6

Basic information

• Product Name: 3,5-dichloro-2-hydroxybenzenesulphonic acid
• Synonyms: 3,5-dichloro-2-hydroxybenzenesulphonic acid;2-Hydroxy-3,5-dichlorobenzenesulfonic acid;54970-72-8 (Mono-hydrochloride salt);Einecs 247-582-4;2-Hydroxy-3,5-dichloro-benzenesulphonic acid
• CAS NO: 26281-43-6
• Molecular Formula: C₆H₄Cl₂O₄S
• Molecular Weight: 243.06456
• EINECS: 247-582-4
• Mol File: 26281-43-6.mol
• Article Data: 4

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.806g/cm³
• CAS DataBase Reference: 3,5-dichloro-2-hydroxybenzenesulphonic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-dichloro-2-hydroxybenzenesulphonic acid(26281-43-6)
• EPA Substance Registry System: 3,5-dichloro-2-hydroxybenzenesulphonic acid(26281-43-6)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 26281-43-6(Hazardous Substances Data)

Usage

General Description

3,5-dichloro-2-hydroxybenzenesulphonic acid, also known as DCHBSA, is a chemical compound containing two chlorine atoms, a hydroxyl group, and a sulfonic acid group attached to a benzene ring. It is used in the production of dyes and pigments, as well as in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. DCHBSA is a strong acid with high water solubility and is commonly used as a pH regulator and stabilizer in various industrial processes. It is important to handle DCHBSA with care, as it can cause skin and eye irritation and may be harmful if ingested or inhaled.

InChI:InChI=1/C6H4Cl2O4S.Na/c7-3-1-4(8)6(9)5(2-3)13(10,11)12;/h1-2,9H,(H,10,11,12);/q;+1/p-1

Upstream product

• 23378-88-3 3,5-dichloro-2-hydroxybenzenesulfonyl chloride 
• 88-06-2 2,4,6-Trichlorophenol 
• 125927-93-7 3,5-dichloro-2-hydroxybenzenesulfinic acid 
• 576-24-9 2,3-dichlorophenol 
• 553-82-2 1,3-dichloro-4-methoxybenzene 
• 120-83-2 2,4-dichlorophenol 

Downstream Products

• 609-89-2 2,4-dichloro-6-nitrophenol 

Relevant articles and documents

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Sulfonation of chloro- and dichloroanisoles with concentrated aqueous sulfuric acid and sulfur trioxide. Demethylation of chloroanisolesulfonic acids in sulfuric acid systems

The nine chloro- and dichloroanisoles have been sulfonated with sulfuric acid.The observed sulfonic acid isomer distributions are determined mainly by the ortho- and para-directing effect of the methoxy substituent.In the reaction with sulfuric acid, the initially formed chloro- and dichloroanisolesulfonic acids are demethylated to give the corresponding phenolsulfonic acids.Demethylation occurs only in those cases where the methoxy substituent is sterically hindered by an o-chloro and/or o-sulfo substituent.Reaction of 2,3- and 3,5-dichloroanisole with fuming sulfuric acid yields initially the 4,6- and 2,4-disulfonic acids, respectively.The disulfonic acids are converted to the corresponding hydrogen sulfates either by direct sulfodemethylation or by protodemethylation followed by subsequent sulfation.The 2,3-dichloro-4,6-disulfophenyl hydrogen sulfate cyclizes to the 1,3,2,4-benzodioxadithiin 2,2,4,4-tetraoxide 4.The sulfonation of the chloro- and dichloroanisoles with SO3 in the solvents nitromethane or CCl3F leads only to sulfodeprotonation.

Communications from the Laboratory of the London Institution. On the action of potassic sulphite on the haloid derivatives of phenol

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