263021-30-3 Usage
Description
N-BOC-4-(METHYLAMINO)BENZOIC ACID is a chemical compound that serves as a pharmaceutical intermediate. It is characterized by the presence of a benzoic acid core with a methylamino group at the 4-position and a BOC (tert-butyloxycarbonyl) protecting group on the nitrogen atom. This structure makes it a versatile building block in the synthesis of various pharmaceuticals and bioactive molecules.
Uses
Used in Pharmaceutical Industry:
N-BOC-4-(METHYLAMINO)BENZOIC ACID is used as a pharmaceutical intermediate for the synthesis of Methotrexate (M260675) derivatives, which are known as antitumor agents. These derivatives have the potential to be developed into effective cancer treatments, targeting the inhibition of key enzymes and pathways involved in tumor growth and progression.
Additionally, as a pharmaceutical intermediate, N-BOC-4-(METHYLAMINO)BENZOIC ACID can be utilized in the development of other bioactive compounds and drug candidates, contributing to the advancement of novel therapeutics for various diseases and medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 263021-30-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,6,3,0,2 and 1 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 263021-30:
(8*2)+(7*6)+(6*3)+(5*0)+(4*2)+(3*1)+(2*3)+(1*0)=93
93 % 10 = 3
So 263021-30-3 is a valid CAS Registry Number.
263021-30-3Relevant articles and documents
Novel Potent Dopamine-Norepinephrine and Triple Reuptake Uptake Inhibitors Based on Asymmetric Pyran Template and Their Molecular Interactions with Monoamine Transporters
Santra, Soumava,Kortagere, Sandhya,Vedachalam, Seenuvasan,Gogoi, Sanjib,Antonio, Tamara,Reith, Maarten E.A.,Dutta, Aloke K.
, p. 1406 - 1418 (2021/05/10)
We have carried out a structural exploration of (2S,4R,5R)-2-(bis(4-fluorophenyl)methyl)-5-((4-methoxybenzyl)amino)tetrahydro-2H-pyran-4-ol (D-473) to investigate the influence of various functional groups on its aromatic ring, the introduction of heteroc
Substituted Pyran Derivatives
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Paragraph 0135; 0136, (2014/10/29)
Certain 3,6-disubstituted and 2, 4, 5-trisubstituted pyran derivatives that exhibit potent activity on monoamine transport systems are provided. The 3, 6 and 2, 4, 5 pyrans are useful in probing the effects of their binding to monoamine transporter system
Structure-based optimization of phenylbutyrate-derived histone deacetylase inhibitors
Lu, Qiang,Wang, Da-Sheng,Chen, Chang-Shi,Hu, Yuan-Dong,Chen, Ching-Shih
, p. 5530 - 5535 (2007/10/03)
Previously, we developed a strategy to develop a novel class of histone deacetylase (HDAC) inhibitors by tethering short-chain fatty acids with Zn 2+-chelating motifs, which led to N-hydroxy-4-(4-phenylbutyryl-amino) benzamide (HTPB), a hydroxa