26305-13-5 Usage
Description
5,6-DIMETHYLURACIL, also known as 2,4-Dihydroxy-5,6-dimethylpyrimidine, is a white to almost white crystalline powder with unique chemical properties. It is a versatile organic compound that serves as a key intermediate in the synthesis of various chemical derivatives.
Uses
Used in Chemical Synthesis:
5,6-DIMETHYLURACIL is used as a starting reagent for the synthesis of mono and polyatomic titanium derivatives. Its unique chemical structure allows for the creation of a wide range of compounds with diverse applications.
Used in Pharmaceutical Industry:
5,6-DIMETHYLURACIL is used as a starting reagent in the synthesis of 2-(4-fluorobenzoyl) substituted pyrimidine derivatives. These derivatives have potential applications in the development of new pharmaceuticals, particularly in the treatment of various diseases and medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 26305-13-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,6,3,0 and 5 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 26305-13:
(7*2)+(6*6)+(5*3)+(4*0)+(3*5)+(2*1)+(1*3)=85
85 % 10 = 5
So 26305-13-5 is a valid CAS Registry Number.
InChI:InChI=1/C6H8N2O2/c1-3-4(2)7-6(10)8-5(3)9/h1-2H3,(H2,7,8,9,10)
26305-13-5Relevant articles and documents
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Endicott,Johnson
, p. 1286,1288 (1941)
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Synthesis of modified uracil and cytosine nucleobases using a microwave-assisted method
Burgula, Laxmi Narayana,Radhakrishnan,Kundu, Lal Mohan
supporting information; experimental part, p. 2639 - 2642 (2012/06/30)
Modified nucleobases and nucleic acids have found many biological and pharmaceutical applications. Here we report a microwave-directed synthesis of a variety of modified uracil and cytosine nucleobases with high yields under solvent-free conditions. The reaction yields were further improved by addition of Lewis acid. The crystal structures of 5-isopropyl-6-methyluracil and 6-phenyluracil were also determined.
New procedures for the synthesis of heterocyclic substituted and 2,4-difunctionalized pyrimidines
Garcia Martinez, Antonio,Herrera Fernandez, Antonio,Moreno Jimenez, Florencio,Munoz Martinez, Pablo J.,Alonso Martin, Cristina,Subramanian, Laksminarayanapuran R.
, p. 7973 - 7982 (2007/10/03)
N-Tosyl-2-and -3-acetylpyrrols 1 or N-tosyl-2-pyrrolidone 5 were condensed with cyano compounds in the presence of triflic anhydride (Tf2O) to yield heteroarylpyrimidines. 2,4-Difunctionalized pyrimidines were obtained by reaction of the corresponding 2,4-bis(methylsulfonyl)pyrimidines with nucleophiles.
