26308-41-8

Basic information

• Product Name: 5-ETHYL-2-METHYL-4-NITRO-2 H-PYRAZOLE-3-CARBOXYLIC ACID
• Synonyms: 3-ETHYL-1-METHYL-4-NITRO-1H-PYRAZOLE-5-CARBOXYLIC ACID;5-ETHYL-2-METHYL-4-NITRO-2 H-PYRAZOLE-3-CARBOXYLIC ACID
• CAS NO: 26308-41-8
• Molecular Formula: C7H9N3O4
• Molecular Weight: 199.16
• Mol File: 26308-41-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 386.3±42.0 °C(Predicted)
• Appearance: /
• Density: 1.52±0.1 g/cm3(Predicted)
• PKA: 2.17±0.50(Predicted)
• CAS DataBase Reference: 5-ETHYL-2-METHYL-4-NITRO-2 H-PYRAZOLE-3-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 5-ETHYL-2-METHYL-4-NITRO-2 H-PYRAZOLE-3-CARBOXYLIC ACID(26308-41-8)
• EPA Substance Registry System: 5-ETHYL-2-METHYL-4-NITRO-2 H-PYRAZOLE-3-CARBOXYLIC ACID(26308-41-8)

Safety Data

• Hazardous Substances Data: 26308-41-8(Hazardous Substances Data)

Relevant articles and documents

Pyrazolodiazepines. 1,3 (and 2,3) dialkyl 4,6 dihydro 8 arylpyrazolo[4,3 e][1,4] diazepin 5 ones as antianxiety agents

A series of 1, 3 (and 2, 3) dialkyl 4, 6 dihydro 8 arylpyrazolo [4, 3 e][1, 4] diazepin 5 ones was synthesized and evaluated for psychotropic activity. Intermediates are new dialkylnitropyrazolyl aryl ketones prepared from dialkylnitropyrazolecarboxylic acids. Many of these pyrazolodiazepines exhibit high CNS activity in animals. One compound, 1 ethyl 4, 6 dihydro 3 methyl 8 phenylpyrazolo [4, 3 e] [1, 4] diazepin 5 (1H) one is about as potent as diazepam as an antianxiety agent with less sedative properties and is being studied in the clinic.