263270-52-6

Basic information

• Product Name: 4-Pyrimidinecarbonyl chloride, 6-chloro- (9CI)
• Synonyms: 4-Pyrimidinecarbonyl chloride, 6-chloro- (9CI);6-chloro-pyrimidine-4-carbonyl chloride;6-chloropyrimidine-4-carboxylic acid chloride
• CAS NO: 263270-52-6
• Molecular Formula: C₅H₂Cl₂N₂O
• Molecular Weight: 176.98818
• Product Categories: ACIDHALIDE
• Mol File: 263270-52-6.mol
• Article Data: 18

Chemical Properties

• Boiling Point: 261.9±20.0 °C(Predicted)
• Appearance: /
• Density: 1.549±0.06 g/cm3(Predicted)
• PKA: -4.89±0.18(Predicted)
• CAS DataBase Reference: 4-Pyrimidinecarbonyl chloride, 6-chloro- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Pyrimidinecarbonyl chloride, 6-chloro- (9CI)(263270-52-6)
• EPA Substance Registry System: 4-Pyrimidinecarbonyl chloride, 6-chloro- (9CI)(263270-52-6)

Safety Data

• Hazardous Substances Data: 263270-52-6(Hazardous Substances Data)

Usage

General Description

4-Pyrimidinecarbonyl chloride, 6-chloro- (9CI) is a chemical compound with the molecular formula C5H3ClN2O. It is a chlorinated derivative of pyrimidinecarbonyl chloride and is commonly used in chemical and pharmaceutical applications. 4-Pyrimidinecarbonyl chloride, 6-chloro- (9CI) is a versatile building block for the synthesis of various pharmaceutical compounds and agrochemicals. It is also used as a chemical intermediate in the production of fine chemicals and research compounds. Additionally, 4-Pyrimidinecarbonyl chloride, 6-chloro- (9CI) has potential biological activity and is being studied for its potential use in drug discovery and development. As with all chemicals, proper handling and storage of this compound are essential for safe use and handling.

Upstream product

• 37131-91-2 6-chloropyrimidine-4-carboxylic acid 
• 6299-87-2 6-hydroxypyrimidine-4-carboxylic acid 

Downstream Products

• 1114592-12-9 6-chloro-N-(2-methylphenyl)pyrimidine-4-carboxamide 
• 1114592-02-7 6-chloro-N-(4-hydroxyphenyl)pyrimidine-4-carboxamide 
• 1114592-18-5 tert-butyl (4-{[(6-chloropyrimidin-4-yl)carbonyl]amino}benzyl)carbamate 
• 1114592-03-8 6-chloro-N-(4-hydroxy-2-methylphenyl)pyrimidine-4-carboxamide 
• 1114592-11-8 6-chloro-pyrimidine-4-carboxylic acid (2-methyl-4-sulfamoyl-phenyl)-amide 
• 1152096-14-4 6-chloro-N-(2-(thiazolo[5,4-b]pyridin-2-yl)phenyl)pyrimidine-4-carboxamide 
• 1114592-30-1 6-chloro-N-(2-methyl-4-(N-methylsulfamoyl)phenyl)pyrimidine-4-carboxamide 
• 1158918-63-8 6-chloro-pyrimidine-4-carboxylic acid-benzyl-(2,2,2-trifluorethyl)-amide 
• 1158918-64-9 6-Chloro-N-phenethyl-N-(2,2,2-trifluoroethyl)pyrimidine-4-carboxamide 
• 1158918-62-7 6-Chloro-N-phenyl-N-(2,2,2-trifluoroethyl)pyrimidine-4-carboxamide 

Relevant articles and documents

BISHETEROCYCLIC CARBONYL SUBSTITUTED DIHYDROPYRAZOLE COMPOUND, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF

Provided are a substituted dihydropyrazole compound as shown in formula I, which compound has a selective inhibitory effect on RIPK1, and a pharmaceutically acceptable salt, a stereoisomer, a solvate or a prodrug thereof, wherein the definition of each group in the formula is detailed in the description. In addition, also disclosed are a pharmaceutical composition containing the compound, and the use thereof in the preparation of a drug for treating RIPK1-related diseases or conditions.

NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES

The present invention relates to novel heteroaryl-triazole compounds of the general formula (I), in which the structural elements X, R1, R2, R3 and R4 have the meaning given in the description, to formulations and compositions comprising such compounds and for their use in the control of animal pests including arthropods and insects in plant protection and to their use for control of ectoparasites on animals.

HETEROCYCLIC AMIDES AS KINASE INHIBITORS

Disclosed are compounds having the formula (I) wherein R1, R2, and R3 are as defined herein, and methods of making and using the same.