263351-43-5

Basic information

• Product Name: (3-IODO-BENZYL)-CARBAMIC ACID TERT-BUTYL ESTER
• Synonyms: tert-Butyl 3-iodobenzylcarbamate;(3-IODO-BENZYL)-CARBAMIC ACID TERT-BUTYL ESTER
• CAS NO: 263351-43-5
• Molecular Formula: C₁₂H₁₆INO₂
• Molecular Weight: 333.16541
• Mol File: 263351-43-5.mol
• Article Data: 13

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (3-IODO-BENZYL)-CARBAMIC ACID TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: (3-IODO-BENZYL)-CARBAMIC ACID TERT-BUTYL ESTER(263351-43-5)
• EPA Substance Registry System: (3-IODO-BENZYL)-CARBAMIC ACID TERT-BUTYL ESTER(263351-43-5)

Safety Data

• Hazardous Substances Data: 263351-43-5(Hazardous Substances Data)

Usage

General Description

"(3-Iodo-benzyl)-carbamic acid tert-butyl ester" is a chemical compound with the formula C11H14INO2. It is a white to off-white solid that is used in various chemical processes and reactions. (3-IODO-BENZYL)-CARBAMIC ACID TERT-BUTYL ESTER is derived from a carbamic acid, and its tert-butyl ester group gives it stability and makes it easy to handle in laboratory settings. The presence of the iodo-benzyl group makes it useful for certain organic synthesis applications. It is important to handle this compound with care and proper safety precautions due to its potentially harmful properties.

Upstream product

• 1228693-09-1 C₂₃H₂₁F₁₇INO₃ 
• 24424-99-5 di-tert-butyl dicarbonate 
• 696-40-2 3-iodobenzylamine 
• 3718-88-5 3-iodobenzylamine hydrochloride 

Downstream Products

• 1222138-87-5 tert-butyl [3-[5-[(2(S)-azetidinyl)methoxy]-3-pyridyl]benzyl]carbamate 
• 828242-06-4 tert-butyl N-[(3-pyrrolidin-1-ylphenyl)methyl]carbamate 
• 175696-70-5 (3-(pyrrolidin-1-yl)phenyl)methanamine 
• 913073-73-1 tert-butyl 3-((trimethylsilyl)ethynyl)benzylcarbamate 
• 1309877-90-4 C₂₆H₂₄ClIN₂O 
• 1283596-51-9 C₁₅H₁₂ClN*ClH 
• 1283596-43-9 C₃₃H₂₈ClN₃O 
• 1222138-84-2 tert-butyl [3-[5-[[1-(benzyloxycarbonyl)-2(S)-azetidinyl]methoxy]-3-pyridyl]benzyl]carbamate 
• 773128-15-7 tert-butyl 3-{6-[4-(4-{(5S)-5-[(acetylamino)methyl]-2-oxo-1,3-oxazolidin-3-yl}-2-fluorophenyl)piperazin-1-yl]-6-oxohex-1-ynyl}phenylcarbamate 

Relevant articles and documents

ADENINE DERIVATIVES AS PROTEIN KINASE INHIBITORS

The present invention relates to a compound suitable for use as a kinase inhibitor according to general formula (I) [compound (C), herein after], or the N- oxide, pharmaceutically acceptable salt, pharmaceutically acceptable solvate, or stereoisomer thereof, formula (I) wherein A, R1, R2, R3, R3', R4, R4', X, Y, Z, T are as defined in the claims. The invention further relates to an in vitro method of inhibiting protein kinase activity which comprises contacting a protein kinase with a compound of formula (I), or the N-oxide, pharmaceutically acceptable salt, pharmaceutically acceptable solvate, or stereoisomer thereof. The invention further relates to the compounds of formula (I) per se, as well as to their use as a medicament, and for use or in a method of treatment of a disease mediated by a protein kinase selected from cancer, inflammatory disorders, cardiovascular diseases, viral induced diseases, circulatory diseases, fibro-proliferative diseases and pain sensitization disorders.

NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS AND THE USES THEREOF

The invention relates to pyridinyl nicotinic acetylcholine receptor ligands, compositions comprising an effective amount of a pyridinyl nicotinic acetylcholine receptor ligand and methods to treat or prevent a condition, such as depression and nicotine dependence, comprising administering to an animal in need thereof an effective amount of a pyridinyl nicotinic acetylcholine receptor ligand.

Synthesis and application of a new fluorous-tagged ammonia equivalent

A novel fluorous-tagged ammonia equivalent has been developed. It is based on a nitrogen-oxygen bond, which can be cleaved in a traceless manner by a molybdenum complex or samarium diiodide. The application in the synthesis of ureas, amides, sulfonamides, and carbamates is described. The scope of the fluo-rous N-O linker is exemplified by the synthesis of itopride, a drug used for the treatment of functional dyspepsia. Itopride was synthesized with the aid of fluorous purification methods and the product was isolated in good overall yield, with high purity.