263546-11-8Relevant articles and documents
HETEROCYCLIC COMPOUNDS AS PRMT5 INHIBITORS
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Paragraph 082; 157; 214, (2020/12/11)
The present disclosure describes novel heterocyclic PRMT5 inhibitors and methods for preparing them. The pharmaceutical compositions comprising such PRMT5 inhibitors and methods of using them for treating cancer, infectious diseases, and other PRMT5 associated disorders are also described.
New synthetic technology for the rapid construction of novel heterocycles - Part 1: The reaction of Dess - Martin periodinane with anilides and related compounds
Nicolaou,Zhong, Yong-Li,Baran, Phil S.
, p. 622 - 625 (2007/10/03)
The unusual behavior of hypervalent iodine reagents, Dess - Martin periodinane and IBX, with an array of anilides leads to the formation of complex heterocycles in only one synthetic operation. Furthermore, the substrates for these transformations are ava