26405-77-6

Basic information

• Product Name: (+/-)-EPINEPHRINE SULFONIC ACID
• Synonyms: (+/-)-EPINEPHRINE SULFONIC ACID;3,4-Dihydroxy-α-[(MethylaMino)Methyl]benzeneMethanesulfonic Acid;3,4-Dihydroxy-α-[(MethylaMino)Methyl]-α-toluenesulfonic Acid;rac-Adrenaline EP Impurity F (Epinephrine Sulfonic Acid)
• CAS NO: 26405-77-6
• Molecular Formula: C₉H₁₃NO₅S
• Molecular Weight: 263.26762
• Product Categories: Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds
• Mol File: 26405-77-6.mol
• Article Data: 3

Chemical Properties

• Melting Point: 263 °C (decomp)(Solv: hydrochloric acid, N (7647-01-0))
• Appearance: White to Light Brown Solid
• Density: 1.510±0.06 g/cm3(Predicted)
• Storage Temp.: Refrigerator
• Solubility: Aqueous Base (Sparingly), DMSO (Slightly, Heated, Sonicated), Water (Slightly, H
• PKA: 0.42±0.50(Predicted)
• CAS DataBase Reference: (+/-)-EPINEPHRINE SULFONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-EPINEPHRINE SULFONIC ACID(26405-77-6)
• EPA Substance Registry System: (+/-)-EPINEPHRINE SULFONIC ACID(26405-77-6)

Safety Data

• Hazardous Substances Data: 26405-77-6(Hazardous Substances Data)

Usage

Description

(+/-)-EPINEPHRINE SULFONIC ACID is a derivative of Epinephrine (E588585) that is formed in injection solutions and eye drops during the sterilization and storage of L-Epinephrine Bitartrate. It is characterized by its beige solid appearance.

Uses

Used in Pharmaceutical Industry:
(+/-)-EPINEPHRINE SULFONIC ACID is used as an active pharmaceutical ingredient in injection solutions and eye drops for various medical applications. Its formation during the sterilization and storage process of L-Epinephrine Bitartrate indicates its potential role in enhancing the therapeutic effects of the parent compound.
Used in Ophthalmology:
In the field of ophthalmology, (+/-)-EPINEPHRINE SULFONIC ACID is used in eye drops to treat various eye conditions. Its presence in eye drop formulations may contribute to the overall efficacy and safety of the treatment.
Used in Research and Development:
(+/-)-EPINEPHRINE SULFONIC ACID is also utilized in research and development for studying its chemical properties, potential applications, and interactions with other compounds. This helps in understanding its role in pharmaceutical formulations and exploring new uses for this derivative.

Upstream product

• 329-65-7 Epinephrine 
• 51-43-4 L-epinephrine 

Relevant articles and documents

Synthesis and adrenoceptor affinity of some highly polar β-substituted catacholamines

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A note on the preparation of 1-(3,4-dihydroxyphenyl)-2-methylamino-ethane sulfonic acid from epinephrine.

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