264608-18-6

Basic information

• Product Name: 6-[(2,2-diphenylethyl)amino]-9H-purine-2-carbonitrile
• Synonyms: 6-[(2,2-diphenylethyl)amino]-9H-purine-2-carbonitrile
• CAS NO: 264608-18-6
• Molecular Weight: 340.387
• Mol File: 264608-18-6.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 6-[(2,2-diphenylethyl)amino]-9H-purine-2-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 6-[(2,2-diphenylethyl)amino]-9H-purine-2-carbonitrile(264608-18-6)
• EPA Substance Registry System: 6-[(2,2-diphenylethyl)amino]-9H-purine-2-carbonitrile(264608-18-6)

Safety Data

• Hazardous Substances Data: 264608-18-6(Hazardous Substances Data)

Upstream product

• 557-21-1 zinc(II) cyanide 
• 264608-14-2 2-chloro-N-(2,2-diphenylethyl)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine 
• 20419-68-5 2,6-dichloro-9-(tetrahydro-2H-pyran-2-yl)-9H-purine 
• 5451-40-1 2,6 dichloropurine 
• 264608-17-5 6-[(2,2-diphenylethyl)amino]-9-(tetrahydro-2H-pyran-2-yl)-9H-purine-2-carbonitrile 
• 73963-98-1 zinc cyanide 

Downstream Products

• 313345-04-9 6-(2,2-diphenyl-ethylamino)-9H-purine-2-carboxylic acid methyl ester 
• 313345-13-0 6-[(2,2-diphenylethyl)amino]-9H-purine-2-carboxylic acid 
• 333333-78-1 (2R,3R,4R,5R)-4-(acetyloxy)-2-[(acetyloxy)methyl]-5-{2-cyano-6-[(2,2-diphenylethyl)amino]-9H-purin-9-yl}tetrahydro-3-furanyl acetate 
• 334701-58-5 (2S,3S,4R,5R)-4-(benzoyloxy)-5-{2-cyano-6-[(2,2-diphenylethyl)amino]-9H-purin-9-yl}-2-[(ethylamino)carbonyl]tetrahydro-3-furanyl benzoate 

Relevant articles and documents

Development of a scaleable process for the synthesis of the A2a agonist, UK-371,104

The development and utilization of a scaleable process for the manufacture of the A2a agonist UK-371,104 (1) is described. Key steps in the synthesis include (i) a palladium-catalyzed cyanation reaction to prepare the nitrile 10, (ii) a telescoped convers

Purine derivatives

The present invention relates to compounds of the formula and pharmaceutically acceptable salts and solvates thereof, to processes for the preparation of, intermediates used in the preparation of, and compositions containing such compounds and the uses of such compounds as adenosine A2a receptor agonists.

Purine derivatives

The present invention relates to compounds of the formula and pharmaceutically acceptable salts and solvates thereof, to processes for the preparation of, intermediates used in the preparation of, and compositions containing such compounds and the uses of