264882-04-4

Basic information

• Product Name: Benzeneacetic acid, a-diazo-, 1-methylethyl ester
• CAS NO: 264882-04-4
• Molecular Formula: C11H12N2O2
• Molecular Weight: 204.228
• Mol File: 264882-04-4.mol
• Article Data: 26

Chemical Properties

• CAS DataBase Reference: Benzeneacetic acid, a-diazo-, 1-methylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetic acid, a-diazo-, 1-methylethyl ester(264882-04-4)
• EPA Substance Registry System: Benzeneacetic acid, a-diazo-, 1-methylethyl ester(264882-04-4)

Safety Data

• Hazardous Substances Data: 264882-04-4(Hazardous Substances Data)

Upstream product

• 39637-68-8 3-Oxo-2,3-diphenyl-propionic acid isopropyl ester 
• 103-82-2 phenylacetic acid 
• 4861-85-2 isopropyl phenylacetate 

Downstream Products

• 89015-27-0 (R)-α-hydroxyphenylacetic acid iso-propyl ester 
• 53439-96-6 (S)-α-hydroxyphenylacetic acid iso-propyl ester 
• 1437744-29-0 (E)-isopropyl 2-(2-(dimethoxyphosphoryl)hydrazono)-2-phenylacetate 
• 60498-68-2 isopropyl 2,2-diphenylacetate 
• 39880-74-5 isopropyl 2-phenyl-2-(phenylamino)acetate 

Relevant articles and documents

Photoinduced Diverse Reactivity of Diazo Compounds with Nitrosoarenes

A diverse reactivity of diazo compounds with nitrosoarene in an oxygen-transfer process and a formal [2 + 2] cycloaddition is reported. Nitosoarene has been exploited as a mild oxygen source to oxidize an in situ generated carbene intermediate under visible-light irradiation. UV-light-mediated in situ generated ketenes react with nitosoarenes to deliver oxazetidine derivatives. These operationally simple processes exemplify a transition-metal-free and catalyst-free protocol to give structurally diverse α-ketoesters or oxazetidines.

Divergent Synthesis of Aziridine and Imidazolidine Frameworks under Blue LED Irradiation

We develop a visible light-promoted divergent cycloaddition of α-diazo esters with hexahydro-1,3,5-triazines, leading to a series of aziridine and imidazolidine frameworks in average good yield, by simply changing the reaction media used. It is noteworthy that the reaction occurs under sole visible light irradiation without the need for exogenous photoredox catalysts. More significantly, a reasonable reaction mechanism was proposed on the basis of the control experiments and density functional theory calculation results.

Visible light and base promoted O-H insertion/cyclization of para-quinone methides with aryl diazoacetates: An approach to 2,3-dihydrobenzofuran derivatives

A visible light and base promoted O-H insertion/cyclization of para-quinone methides with aryl diazoacetates is developed. This one-pot two step reaction offers a mild and efficient approach for the synthesis of biologically important 2,3-dihydrobenzofuran derivatives in good yields and moderate diastereoselectivities.