26638-45-9

Basic information

• Product Name: 2-{[METHYL(PHENYL)AMINO]SULFONYL}BENZOIC ACID
• Synonyms: Benzoicacid, o-(methylphenylsulfamoyl)- (8CI)
• CAS NO: 26638-45-9
• Molecular Formula: C₁₄H₁₃NO₄S
• Molecular Weight: 291.32
• Mol File: 26638-45-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 482.6°Cat760mmHg
• Flash Point: 245.7°C
• Appearance: /
• Density: 1.389g/cm³
• Vapor Pressure: 4E-10mmHg at 25°C
• CAS DataBase Reference: 2-{[METHYL(PHENYL)AMINO]SULFONYL}BENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{[METHYL(PHENYL)AMINO]SULFONYL}BENZOIC ACID(26638-45-9)
• EPA Substance Registry System: 2-{[METHYL(PHENYL)AMINO]SULFONYL}BENZOIC ACID(26638-45-9)

Safety Data

• Hazardous Substances Data: 26638-45-9(Hazardous Substances Data)

Usage

Properties

1. Classification: Non-steroidal anti-inflammatory drug (NSAID)
2. Common Name: Meclofenamic acid
3. Uses: Treatment of mild to moderate pain and inflammation
4. Mechanism of Action: Inhibits the production of certain pain and inflammation-causing chemicals in the body
5. Chemical Structure: Structurally similar to other NSAIDs like aspirin and ibuprofen
6. Class: Member of the anthranilic acid derivatives class of NSAIDs

Specific Content

1. Treatment: Used for arthritis, menstrual cramps, and acute musculoskeletal pain
2. Safety: Important to use under the guidance of a healthcare professional to avoid serious side effects
3. Chemical Name: 2-[methyl(phenyl)amino]sulfonylbenzoic acid
4. Commonly Known As: Meclofenamic acid

InChI:InChI=1/C14H13NO4S/c1-15(11-7-3-2-4-8-11)20(18,19)13-10-6-5-9-12(13)14(16)17/h2-10H,1H3,(H,16,17)/p-1

Upstream product

• 63914-81-8 chlorosulphonyl-benzoic acid 
• 100-61-8 N-methylaniline 
• 26638-44-8 methyl 2-[(methylanilino)sulfonyl]benzoate 

Downstream Products

• 87223-38-9 2-(Methyl-phenyl-sulfamoyl)-benzoyl chloride 
• 632-25-7 2-sulfobenzoic acid 

Relevant articles and documents

Silver-catalyzed intramolecular oxidative decarboxylative C-H arylation reactions for synthesis of biaryl sultams

A mild, versatile and efficient method to form biaryl sultams through silver-catalyzed intramolecular oxidative decarboxylative C-H arylation reactions has been developed. The present protocol features a broad substrate scope and very good tolerance to di

STRUCTURE AND REACTIVITY IN INTRAMOLECULAR CATALYSIS. CATALYSIS OF SULFONAMIDE HYDROLYSIS BY THE NEIGHBORING CARBOXY GROUP.

A report is presented on kinetic data for the intramolecular carboxy-catalyzed hydrolysis of 26 sulfonamides in water and in some mixed aqueous solvents. The effective molarity of the carboxyl group is very high (up to ca. 10**8 M) but depends markedly on the structure of the sulfonamide. Substituent effects within a series of 4- and 5-substituted 2-carboxy-N,N-dimethylbenzenesulfonamides are interpreted in terms of nucleophilic catalysis. The role of nonbonded interactions in the initial state and in the transition state is discussed. By using X-ray structural data where available, strain effects have been elucidated for a series of sulfonamides in which the sulfonamide and carboxyl groups are held cis to each other. Striking differences from the corresponding carboxamide systems are attributed to differences in transition state geometries and steric effects.