26878-13-7

Basic information

• Product Name: methyl 2-oxo-2-(thiophen-2-yl)acetate
• Synonyms: methyl 2-oxo-2-(thiophen-2-yl)acetate;Aclidinium Impurity 1;Methyl 2-Oxo-2-(Thiophen-2-Yl)Acetate(WXC00019)
• CAS NO: 26878-13-7
• Molecular Formula: C₇H₆O₃S
• Molecular Weight: 170.18574
• Mol File: 26878-13-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 100-102 °C(Press: 0.8 Torr)
• Appearance: /
• Density: 1.304±0.06 g/cm3(Predicted)
• CAS DataBase Reference: methyl 2-oxo-2-(thiophen-2-yl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-oxo-2-(thiophen-2-yl)acetate(26878-13-7)
• EPA Substance Registry System: methyl 2-oxo-2-(thiophen-2-yl)acetate(26878-13-7)

Safety Data

• Hazardous Substances Data: 26878-13-7(Hazardous Substances Data)

Usage

Description

Methyl 2-oxo-2-(thiophen-2-yl)acetate is a chemical compound with the formula C8H8O3S. It is an acetate derivative that features a methyl group, a carbonyl group, and a thiophene ring. methyl 2-oxo-2-(thiophen-2-yl)acetate is characterized by its yellowish appearance and distinctive odor. It is widely utilized in various industries, including pharmaceuticals, agrochemicals, and as a component in flavoring and fragrances. Additionally, it serves as a valuable building block in organic synthesis, particularly for the creation of heterocyclic compounds. Due to its potentially hazardous nature, it is essential to handle this chemical with caution.

Uses

Used in Pharmaceutical Industry:
Methyl 2-oxo-2-(thiophen-2-yl)acetate is used as an intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs and enhance the properties of existing ones.
Used in Agrochemical Industry:
In the agrochemical sector, methyl 2-oxo-2-(thiophen-2-yl)acetate is employed as a precursor in the production of agrochemicals, helping to improve crop protection and yield.
Used in Flavoring and Fragrance Industry:
Methyl 2-oxo-2-(thiophen-2-yl)acetate is used as a flavoring and fragrance ingredient, capitalizing on its distinctive odor to create unique scents and tastes in various consumer products.
Used in Organic Synthesis:
As a building block in organic synthesis, methyl 2-oxo-2-(thiophen-2-yl)acetate is used for the formation of heterocyclic compounds, which are essential in the development of complex organic molecules and have applications in various fields, including medicine and materials science.

Upstream product

• 186581-53-3 diazomethane 
• 3437-95-4 2-Iodothiophene 
• 201230-82-2 carbon monoxide 

Downstream Products

• 693-25-4 n-pentylmagnesium bromide 
• 440676-26-6 methyl 2-cyclohexyl-2-hydroxy-2-(thiophen-2-yl)acetate 
• 1586007-49-9 (E)-methyl 2-(4-methoxyphenylimino)-2-(thiophen-2-yl)acetate 
• 1586007-75-1 (Z)-methyl 2-(4-methoxyphenylimino)-2-(thiophen-2-yl)acetate 
• 10471-74-6 1-phenyl-3-(thiophen-2-yl)propane-1,3-dione 
• 21124-40-3 D,L-(2-thienyl)glycine 
• 26447-85-8 hydroxy-di-thiophen-2-yl-acetic acid methyl ester 
• 86582-52-7 N-benzyl-2-oxo-2-(thiophen-2-yl)acetamide 
• 1450631-21-6 C₁₉H₁₇NO₂S 
• 1450631-23-8 C₁₇H₁₅NO₂S₂ 
• 1344689-94-6 methyl 2-hydroxy-4-(4-methoxyphenyl)-2-(thiophen-2-yl)but-3-ynoate 
• 151259-53-9 Thiophen-2-yl-(toluene-4-sulfonylamino)-acetic acid methyl ester 
• 151259-50-6 methyl N-p-tolylsulfonyl-2-imino-2-(2-thienyl)acetate 
• 4075-60-9 oxo-thiophen-2-yl-acetyl chloride 

Relevant articles and documents

Palladium(II) Complex-catalysed Formation of α-Keto Acids via Double Carbonylation of Organic Halides

Organic halides are doubly carbonylated in the presence of water using the PdCl2(PPh3)2 catalyst leading to the formation of α-keto acids.