26902-80-7

Basic information

• Product Name: 1,1,1-trifluoro-2-nonanol
• Synonyms: 1,1,1-trifluoro-2-nonanol
• CAS NO: 26902-80-7
• Molecular Weight: 198.229
• Mol File: 26902-80-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1,1,1-trifluoro-2-nonanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1,1-trifluoro-2-nonanol(26902-80-7)
• EPA Substance Registry System: 1,1,1-trifluoro-2-nonanol(26902-80-7)

Safety Data

• Hazardous Substances Data: 26902-80-7(Hazardous Substances Data)

Usage

Physical state

Colorless liquid

Boiling point

164 degrees Celsius

Industrial uses

a. Production of pharmaceuticals
b. Production of pesticides
c. Production of surfactants

Additional uses

a. Solvent
b. Intermediate in the synthesis of other chemicals

Health hazards

a. Skin and eye irritant
b. Respiratory and central nervous system effects at high exposure levels

Safety precautions

Handle with caution and follow proper safety measures when working with this chemical.

Upstream product

• 13125-66-1 n-heptylmagnesium bromide 
• 124-13-0 Octanal 
• 75-63-8 Bromotrifluoromethane 
• 26902-66-9 1,1,1-trifluorononan-2-one 

Relevant articles and documents

N-heterocyclic carbene catalyzed trifluoromethylation of carbonyl compounds

(Chemical Equation Presented) A novel N-heterocyclic carbene (NHC) catalyzed trifluoromethylation reaction of carbonyl compounds was discovered. Both enolizable and nonenolizable aldehydes and α-keto esters undergo facile trifluoromethylation with TMSCF3 at room temperature in the presence of only 0.5-1 mol % of the commercially available NHC (1), providing CF3-substituted alcohols in good yields. Selective trifluoromethylation of aldehydes over ketones can be achieved under NHC catalysis. These conditions are mild and simple and tolerate a variety of functional groups.

Efficient synthesis of optically pure 1,1,1-trifluoro-2-alkanols through lipase-catalyzed acylation in organic media

Lipase-catalyzed esterification was successfully utilized for the optical resolution of 1,1,1-trifluoro-2-alkanol 1 when racemic 1 was treated with lipase from Candida antarctica in hexane in the presence of molecular sieves (4 A) to provide the corresponding (S)-acetate 2 in an optically pure state. Alkanol 1 is known as an important component of liquid crystal compounds which display remarkable ferroelectric liquid crystal (FLC) characteristics. Five types of optically pure alkanols, i.e., 1,1,1-trifluoro-2-octanol (1a), 1,1,1-trifluoro-2-nonanol (1b), 1,1,1-trifluoro-2-decanol (1c), 1,1,1-trifluoro-2-undecanol (1d), and 1,1,1-trifluoro-8-(benzyloxy)-2-octanol (1e), were thus obtained by the lipase-catalyzed acylation.

ELECTROSYNTHESIS OF ALCOHOLS FROM ORGANIC HALIDES AND KETONES OR ALDEHYDES

The electrosynthesis of a wide range of alcohols from organic halides and ketones or aldehydes is achieved under simple and mild conditions in an undivided electrolytic cell using different sacrificial anodes.