26933-59-5

Basic information

• Product Name: Furo[3,4-b]pyridin-5(7H)-one, 7-(phenylmethylene)-
• CAS NO: 26933-59-5
• Molecular Formula: C14H9NO2
• Molecular Weight: 223.231
• Mol File: 26933-59-5.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Furo[3,4-b]pyridin-5(7H)-one, 7-(phenylmethylene)-(CAS DataBase Reference)
• NIST Chemistry Reference: Furo[3,4-b]pyridin-5(7H)-one, 7-(phenylmethylene)-(26933-59-5)
• EPA Substance Registry System: Furo[3,4-b]pyridin-5(7H)-one, 7-(phenylmethylene)-(26933-59-5)

Safety Data

• Hazardous Substances Data: 26933-59-5(Hazardous Substances Data)

Upstream product

• 131169-57-8 2-Phenylethynyl-nicotinic acid 
• 131169-59-0 6,7-dihydro-7-benzyl-7-hydroxy-5H-furo<3,4-b>pyridin-5-one 
• 118159-94-7 2-phenylethynylpyridine-3-carbonitrile 
• 222167-31-9 2-(2-phenylethynyl)pyridine-3-carbaldehyde 
• 35905-85-2 2-bromonicotinic acid 
• 536-74-3 phenylacetylene 
• 103-82-2 phenylacetic acid 
• 699-98-9 Pyridine-2,3-dicarboxylic anhydride 
• 128071-75-0 2-bromopyridine-3-carboxaldehyde 

Downstream Products

• 139157-37-2 6-(4-Methoxy-phenyl)-7-[1-phenyl-meth-(Z)-ylidene]-6,7-dihydro-pyrrolo[3,4-b]pyridin-5-one 
• 139157-35-0 6-Phenyl-7-[1-phenyl-meth-(Z)-ylidene]-6,7-dihydro-pyrrolo[3,4-b]pyridin-5-one 
• 139157-30-5 9-Phenyl-pyrido[2,3-a]pyrrolizine-5,8-dione 
• 139157-31-6 7-Methyl-9-phenyl-pyrido[2,3-a]pyrrolizine-5,8-dione 
• 139157-33-8 7-Isobutyl-9-phenyl-pyrido[2,3-a]pyrrolizine-5,8-dione 
• 139157-36-1 6-(4-Chloro-phenyl)-7-[1-phenyl-meth-(Z)-ylidene]-6,7-dihydro-pyrrolo[3,4-b]pyridin-5-one 

Relevant articles and documents

Pd-free Sonogashira coupling: One pot synthesis of phthalide via domino Sonogashira coupling and 5-exo-dig cyclization

Phthalides have been synthesized exclusively in one pot via Pd-free Sonogashira coupling. A Cu-catalyzed domino Sonogashira coupling and 5-exo-dig cyclization between suitable substituted ortho-bromobenzoic acids and terminal alkynes afforded phthalides in good yields under mild reaction conditions.

NHC-catalyzed oxidative cyclization reactions of 2-alkynylbenzaldehydes under aerobic conditions: Synthesis of O-Heterocycles

Chemical equations presented. An NHC-catalyzed, regio- and stereoselective oxidative cyclization of o-alkynylbenzaldehydes bearing an unactivated alkyne moiety as an internal electrophile has been developed to afford phthalides and isocoumarins. A single organocatalytic system enabled two sequential C-O bond formations to take place in an atom economical manner via highly efficient dual activation. Molecular oxygen in air could be utilized as a source of an oxygen atom for the oxidation of aldehydes to the corresponding benzoic acids under our newly developed reagent system.

SYNTHESIS OF SOME NEW N-SUBSTITUTED QUINOLIMIDES WITH ANTIBACTERIAL ACTIVITY

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