26956-43-4

Basic information

• Product Name: 4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE
• Synonyms: FURO[3,2-C]PYRIDIN-4(5H)-ONE;4-OXO-4,5-DIHYDROFURO[3,2-C]PYRIDINE;4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE;4,5-Dihyro-4-Oxofuro[3,2]Pyridine;4H,5H-furo[3,2-c]pyridin-4-one;Furo[3,2-c]pyridin-4-ol;5H-Furo[3,2-c]pyridin-4-one
• CAS NO: 26956-43-4
• Molecular Formula: C₇H₅NO₂
• Molecular Weight: 135.12
• EINECS: 125-856-9
• Product Categories: Fused Ring Systems
• Mol File: 26956-43-4.mol
• Article Data: 14

Chemical Properties

• Melting Point: 202-204 °C
• Boiling Point: 372.805 °C at 760 mmHg
• Flash Point: 179.266 °C
• Appearance: /
• Density: 1.288 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.558
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 12.11±0.20(Predicted)
• CAS DataBase Reference: 4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE(26956-43-4)
• EPA Substance Registry System: 4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE(26956-43-4)

Safety Data

• Hazard Codes: T
• Statements: 25
• Safety Statements: 45
• RIDADR: 2811
• HazardClass: 6.1
• PackingGroup: Ⅲ
• Hazardous Substances Data: 26956-43-4(Hazardous Substances Data)

Usage

General Description

4,5-Dihydro-4-oxofuro[3,2-c]pyridine is a chemical compound belonging to the furo[3,2-c]pyridine class. It is a heterocyclic compound with a bicyclic structure, containing a furan ring fused to a pyridine ring. 4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE is often used as a building block in the synthesis of various pharmaceuticals, agrochemicals, and materials. Its unique structure and reactivity make it valuable in organic synthesis, particularly in the development of new drugs and functional materials. Additionally, research suggests that 4,5-dihydro-4-oxofuro[3,2-c]pyridine derivatives may have potential therapeutic applications, such as antiviral and antibacterial properties. However, further studies are needed to fully understand its biological activities and potential uses.

InChI:InChI=1/C7H5NO2/c9-7-5-2-4-10-6(5)1-3-8-7/h1-4H,(H,8,9)

Upstream product

• 31270-80-1 4-chlorofuro[3,2-c]pyridine 
• 53282-12-5 ethyl (E)-3-(2-furyl)prop-2-enoate 
• 98-01-1 furfural 
• 541-41-3 chloroformic acid ethyl ester 
• 539-47-9 3-(2-furyl)acrylic acid 
• 119924-26-4 (E)-3-(2-furanyl)-2-propenoyl azide 
• 46265-05-8 2-(2-amino-1-hydroxy-ethyl)-furan-3-carboxylic acid ethyl ester 
• 29080-01-1 β-(2-Furan)-vinylisocyanat 
• 59898-36-1 (E)-3-Furan-2-yl-acryloyl azide 
• 33007-15-7 7-hydroxy-6,7-dihydro-5H-furo[3,2-c]pyridin-4-one 
• 539-47-9 3-(fur-2-yl)crotonic acid 
• 20689-54-7 3-furanylacryloyl chloride 
• 57420-06-1 furo<3,2-c>pyridine N-oxide 
• 108-24-7 acetic anhydride 

Downstream Products

• 106260-91-7 4-<4-<4-(4-furo<3,2-c>pyridinyl)-1-piperazinyl>butyl>-3,5-morpholinedione 
• 106261-12-5 1-(4-Fluoro-phenyl)-4-(4-furo[3,2-c]pyridin-4-yl-piperazin-1-yl)-butan-1-ol; hydrochloride 
• 81078-84-4 4-(1-piperazinyl)furo<3,2-c>pyridine 
• 31270-80-1 4-chlorofuro[3,2-c]pyridine 
• 1613479-47-2 C₁₃H₇F₂NO₂ 
• 86518-10-7 acetyl-2 chloro-4 furo<3,2-c>pyridine 
• 84400-99-7 7-Chlorofuro[2,3-c]pyridine 
• 1175300-09-0 C₁₅H₁₁BrCl₂N₂O₂ 
• 1175300-07-8 3-bromo-7-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]furo[3,2-c]pyridin-6-ylamine 
• 1175300-08-9 C₁₅H₉BrCl₂N₂O₄ 
• 1175296-53-3 3-Bromo-7-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-6-nitrofuro[3,2-c]-pyridine 
• 1175296-51-1 7-[1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-6-nitrofuro[3,2-c]pyridine 
• 1175300-11-4 7-[1-(2-chloro-5-fluorophenyl)ethoxy]-3-(1-piperidin-4-yl-1H-pyrazol-4-yl)-furo[3,2-c]pyridin-6-ylamine 

Relevant articles and documents

Organic metal compound and organic light-emitting device

Organic metal compounds and organic light-emitting devices employing the same are provided. The organic metal compound has a chemical structure of Formula (I) or Formula (II): In particular, one of the following two conditions (1) and (2) is met: (1) R1 is deuterium or C1-6 deuterated alkyl group, when R3 and R4 are independently hydrogen, halogen, C1-6 alkyl group, C1-6 fluoroalkyl or C3-12 heteroaryl group; and (2) R1 is hydrogen, deuterium, C1-6 alkyl group, C1-6 deuterated alkyl group, C3-12 heteroaryl group, or C6-12 aryl group, when at least one of R3 and R4 is C6-12 aryl group or C6-12 fluoroaryl group.

A novel furo[3,2-: C] pyridine-based iridium complex for high-performance organic light-emitting diodes with over 30% external quantum efficiency

A novel furo[3,2-c]pyridine based Ir complex, namely (pfupy)2Ir(acac), has been developed by replacing sulfur with oxygen in the C^N ligand. Compared with the thiophene-containing (pthpy)2Ir(acac), the LUMO level is elevated while the HOMO level remains almost unchanged for the resultant furan-containing (pfupy)2Ir(acac). As a consequence, the emissive maximum is blue-shifted from 556 nm of (pthpy)2Ir(acac) to 538 nm of (pfupy)2Ir(acac) together with an improved photoluminescence quantum yield of 0.80. The corresponding device based on (pfupy)2Ir(acac) realizes a record-high external quantum efficiency (EQE) of 30.5% (110.5 cd A-1) without any out-coupling technology. Even at a luminance of 1000 and 5000 cd m-2, the EQE still remains at 26.6% (96.4 cd A-1) and 25.6% (92.7 cd A-1), respectively, indicative of the gentle efficiency roll-off. The results clearly demonstrate the great potential of furan-based functional materials applied in OLEDs.

IMIDAZOTHIADIAZOLE DERIVATIVES AS PROTEASE ACTIVATED RECEPTOR 4 (PAR4) INHIBITORS FOR TREATING PLATELET AGGREGATION

The present invention provides imidazothiadiazole compounds of Formula (I) wherein A, B, D, Rx, R1, R2, R3, X1, X2 and s are as defined herein, or a stereoisomer, tautomer, pharmaceutically acceptable salt or solvate form thereof, wherein all of the variables are as defined herein. These compounds are inhibitors of platelet aggregation and thus can be used as medicaments.