26960-80-5

Basic information

• Product Name: methyl 4-dodecylthiobenzoate
• Synonyms: methyl 4-dodecylthiobenzoate
• CAS NO: 26960-80-5
• Molecular Weight: 336.539
• Mol File: 26960-80-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: methyl 4-dodecylthiobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-dodecylthiobenzoate(26960-80-5)
• EPA Substance Registry System: methyl 4-dodecylthiobenzoate(26960-80-5)

Safety Data

• Hazardous Substances Data: 26960-80-5(Hazardous Substances Data)

Upstream product

• 403-33-8 methyl 4-flurobenzoate 
• 112-55-0 1-dodecylthiol 
• 619-50-1 4-nitrobenzoic acid methyl ester 

Downstream Products

• 720-75-2 methyl 4-phenylbenzoate 

Relevant articles and documents

Palladium-Catalyzed Zinc-Amide-Mediated C-H Arylation of Fluoroarenes and Heteroarenes with Aryl Sulfides

C-H arylation of polyfluoroarenes and heteroarenes with aryl sulfides proceeds smoothly with the aid of a palladium-N-heterocyclic carbene catalyst. A bulky zinc amide, TMPZnCl an effective base to generate the corresponding arylzinc species in situ. This arylation protocol is practically much easier to perform than our previous method, which necessitates preparation of the arylzinc reagents in advance from the corresponding aryl halides. Aryl sulfides that are prepared through sulfur-specific reactions, such as SNAr sulfanylation and extended Pummerer reactions, undergo this direct arylation, offering interesting transformations that are otherwise difficult to achieve with conventional halogen-based organic synthesis.

Nucleophilic aromatic substitution reaction of nitroarenes with alkyl- or arylthio groups in dimethyl sulfoxide by means of cesium carbonate

Treatment of nitroarenes having electron-withdrawing groups at the ortho or para position with alkanethiol in the presence of cesium carbonate in dimethyl sulfoxide at 25°C leads to nucleophilic displacement of the nitro group with the alkylthio group. Cesium carbonate is superior to other bases such as potassium carbonate, sodium carbonate, and triethylamine. The cesium-mediated nucleophilic aromatic substitution reaction provides a mild yet powerful and user-friendly protocol for the synthesis of aryl sulfides.