269726-83-2 Usage
General Description
BOC-(R)-3-AMINO-4-(3-CYANO-PHENYL)-BUTYRIC ACID is a chemical compound with the molecular formula C16H20N2O4. It is a white to off-white powder that is primarily used as a research chemical and biochemical. BOC-(R)-3-AMINO-4-(3-CYANO-PHENYL)-BUTYRIC ACID is an amino acid derivative that contains a BOC (tert-butyloxycarbonyl) protecting group, which helps to increase stability and solubility. It is commonly used in the synthesis of peptides and other pharmaceutical compounds. BOC-(R)-3-AMINO-4-(3-CYANO-PHENYL)-BUTYRIC ACID is also utilized as a building block for the creation of new drugs and in biochemical research.
Check Digit Verification of cas no
The CAS Registry Mumber 269726-83-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,6,9,7,2 and 6 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 269726-83:
(8*2)+(7*6)+(6*9)+(5*7)+(4*2)+(3*6)+(2*8)+(1*3)=192
192 % 10 = 2
So 269726-83-2 is a valid CAS Registry Number.
InChI:InChI=1/C16H20N2O4/c1-16(2,3)22-15(21)18-13(9-14(19)20)8-11-5-4-6-12(7-11)10-17/h4-7,13H,8-9H2,1-3H3,(H,18,21)(H,19,20)/t13-/m1/s1
269726-83-2Relevant articles and documents
Discovery of potent and selective β-homophenylalanine based dipeptidyl peptidase IV inhibitors
Xu, Jinyou,Ok, Hyun O.,Gonzalez, Edward J.,Colwell Jr., Lawrence F.,Habulihaz, Bahanu,He, Huaibing,Leiting, Barbara,Lyons, Kathryn A.,Marsilio, Frank,Patel, Reshma A.,Wu, Joseph K.,Thornberry, Nancy A.,Weber, Ann E.,Parmee, Emma R.
, p. 4759 - 4762 (2007/10/03)
Modification of in-house screening lead β-aminoacyl proline 8 gave an equipotent thiazolidide 9. Extensive SAR studies on the phenyl ring of 9 led to the discovery of a novel series of potent and selective DP-IV inhibitors. Introduction of a fluorine at the 2-position proved to be crucial for the potency of this series. The 2,5-difluoro (22q) and 2,4,5-trifluoro (22t) analogues were potent inhibitors of DP-IV (IC50 = 270, 119 nM, respectively).
