270-68-8

Basic information

• Product Name: 2H-Isoindole
• Synonyms: 2-Benzazole;2H-Isoindole
• CAS NO: 270-68-8
• Molecular Formula: C₈H₇N
• Molecular Weight: 117.15
• Mol File: 270-68-8.mol
• Article Data: 1

Chemical Properties

• Melting Point: 149.5-150 °C
• Boiling Point: 275.4°C at 760 mmHg
• Flash Point: 111.9°C
• Appearance: /
• Density: 1.149g/cm³
• Vapor Pressure: 0.00858mmHg at 25°C
• Refractive Index: 1.68
• PKA: 17.00±0.30(Predicted)
• CAS DataBase Reference: 2H-Isoindole(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Isoindole(270-68-8)
• EPA Substance Registry System: 2H-Isoindole(270-68-8)

Safety Data

• Hazardous Substances Data: 270-68-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H7N/c1-2-4-8-6-9-5-7(8)3-1/h1-6,9H

Upstream product

• 17300-02-6 1,2-benzenedimethanamine 

Downstream Products

• 112966-09-3 exo-1,2,3,4-Tetrahydro-N-(4-nitrophenyl)-1,4-imino-2,3-naphthalindicarboximid 
• 112897-90-2 endo-1,2,3,4-Tetrahydro-N-(4-nitrophenyl)-1,4-imino-2,3-naphthalindicarboximid 
• 112966-10-6 exo-1,2,3,4-Tetrahydro-N-(4-phenyldiazenyl)-1,4-imino-2,3-naphthalindicarboximid 
• 112897-91-3 endo-1,2,3,4-Tetrahydro-N-(4-phenyldiazenyl)-1,4-imino-2,3-naphthalindicarboximid 
• 112966-08-2 exo-1,2,3,4-Tetrahydro-N-(4-methoxyphenyl)-1,4-imino-2,3-naphthalindicarboximid 
• 112897-89-9 endo-1,2,3,4-Tetrahydro-N-(4-methoxyphenyl)-1,4-imino-2,3-naphthalindicarboximid 
• 91199-17-6 exo-1,2,3,4-Tetrahydro-N-(4-methylphenyl)-1,4-imino-2,3-naphthalindicarboximid 
• 91129-13-4 endo-1,2,3,4-Tetrahydro-N-(4-methylphenyl)-1,4-imino-2,3-naphthalindicarboximid 
• 37914-46-8 exo-1,2,3,4-Tetrahydro-N-phenyl-1,4-imino-2,3-naphthalindicarboximid 
• 49616-47-9 endo-1,2,3,4-Tetrahydro-N-phenyl-1,4-imino-2,3-naphthalindicarboximid 
• 1434246-93-1 ethyl 4-(2H-isoindoline-2-carboxamido)benzoate 
• 141259-38-3 (tetrahydrofuran)(meso-tetraphenyltetrabenzoporphyrin)zinc(II) 

Relevant articles and documents

Intramolecular condensation of 1,2-C6H4(CH 2RH)2 (R = O, S, and NH) to yield heterocyclic compounds over halide-cluster catalysts

1,2-Benzenedimethanol was reacted under a helium stream in the presence of [(Nb6Cl12)Cl2(H2O) 4]·4H2O supported on silica gel. When the temperature was raised above 200 °C, catalytic activity of the cluster for cyclization appeared, yielding 1,3-dihydroisobenzofuran in 91% selectivity at 350 °C. The corresponding halide clusters of tantalum and tungsten also catalyzed the reaction. cis-1,2-Cyclohexanedimethanol and 1,4-butanediol exclusively produced the corresponding furans. 1,2-Benzenedimethanamine and 1,2-benzenedimethanethiol selectively afforded isoindoline and 1,3-dihydrobenzo[c]thiophene, respectively.