27044-91-3

Basic information

• Product Name: 4-phenyl-3,4,7,8-tetrahydro-2H-chromene-2,5(6H)-dione
• Synonyms: 4-phenyl-3,4,7,8-tetrahydro-2H-chromene-2,5(6H)-dione
• CAS NO: 27044-91-3
• Molecular Weight: 242.274
• Mol File: 27044-91-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-phenyl-3,4,7,8-tetrahydro-2H-chromene-2,5(6H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 4-phenyl-3,4,7,8-tetrahydro-2H-chromene-2,5(6H)-dione(27044-91-3)
• EPA Substance Registry System: 4-phenyl-3,4,7,8-tetrahydro-2H-chromene-2,5(6H)-dione(27044-91-3)

Safety Data

• Hazardous Substances Data: 27044-91-3(Hazardous Substances Data)

Upstream product

• 102-92-1 Cinnamoyl chloride 
• 504-02-9 1,3-cylohexanedione 
• 201230-82-2 carbon monoxide 
• 42599-24-6 E-styryl iodide 
• 130110-63-3 3-Oxocyclohex-1-enyl cinnamate 

Relevant articles and documents

Enantioselective synthesis of enol lactones from tandem Michael addition/lactonization catalyzed by a chiral squaramide catalyst

The enantioselective tandem Michael addition reaction of dimedone and related 1,3-dicarbonyl compounds with α,β-unsaturated N-acylated succinimides catalyzed by a chiral squaramide catalyst has been investigated. This reaction provides a new approach for the synthesis of chiral enol lactones in good yields with moderate to high enantioselectivities (up to 88% ee) through the enantioselective Michael addition followed by lactonization and removal of the succinimide auxiliary.

SYNTHESIS OF ENOL ESTERS AND ENOL LACTONES VIA PALLADIUM-CATALYZED CARBONYLATION OF ARYL AND ALKENYL HALIDES

Acylpalladium species derivable via oxidative addition of a Pd-phosphine complex with aryl and alkenyl iodides and CO insertion can react, either intramolecularly or intermolecularly, with enolates generated in situ to give the corresponding enol esters a