2706-65-2

Basic information

• Product Name: N',N'',N'''-Tetraacetylchitotetraose
• Synonyms: CHITOTETRAOSE, TETRA-N-ACETYL;GLCNAC1-B-4GLCNAC1-B-4GLCNAC1-B-4GLCNAC;GLCNAC-BETA1-4GLCNAC-BETA1-4GLCNAC-BETA1-4GLCNAC;N,N',N'',N'''-TETRAACETYL CHITOTETRAOSE;TETRA-(N-ACETYL) CHITOTETRAOSE;NI, NII, NIII, NIV-Tetraacetylchitotetraose;N-acetylated Chitotetraose;O-2-(Acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-4)-O-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-4)-O-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-4)-2-(acetylamino)-2-deoxy-D-glucose
• CAS NO: 2706-65-2
• Molecular Formula: C₃₂H₅₄N₄O₂₁
• Molecular Weight: 830.79
• Product Categories: Oligosaccharides
• Mol File: 2706-65-2.mol
• Article Data: 1

Chemical Properties

• Melting Point: >200°C dec.
• Boiling Point: 1338.1°Cat760mmHg
• Flash Point: 763.1°C
• Appearance: /
• Density: 1.57g/cm³
• Storage Temp.: −20°C
• Solubility: Water (Slightly)
• Stability: Store in freezer
• CAS DataBase Reference: N',N'',N'''-Tetraacetylchitotetraose(CAS DataBase Reference)
• NIST Chemistry Reference: N',N'',N'''-Tetraacetylchitotetraose(2706-65-2)
• EPA Substance Registry System: N',N'',N'''-Tetraacetylchitotetraose(2706-65-2)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 2706-65-2(Hazardous Substances Data)

Usage

Description

N',N'',N'''-Tetraacetylchitotetraose, also known as TAC, is a chitin-derived compound prepared through acetolysis. It is an off-white solid with unique chemical properties that have been studied for their potential applications, particularly in the field of medicine.

Uses

Used in Pharmaceutical Industry:
N',N'',N'''-Tetraacetylchitotetraose is used as an anti-tumor agent for its demonstrated anti-tumor effects. Studies have shown that this compound can effectively target and inhibit the growth of cancer cells, making it a promising candidate for the development of novel cancer treatments.
Used in Research and Development:
In addition to its potential pharmaceutical applications, N',N'',N'''-Tetraacetylchitotetraose is also utilized in research and development for the study of chitin-derived compounds and their potential applications in various fields, including medicine, agriculture, and material science. Its unique chemical properties and off-white solid form make it an interesting subject for further investigation and experimentation.

Relevant articles and documents

Concise preparation of biologically active chitooligosaccharides

Chitooligosaccharides (COSs) have demonstrated a diverse array of biological activities. Here we report a concise preparation method for tetra-N-acetyl-chitotetraose and penta-N-acetyl-chitopentaose. The FACE analysis showed that the partially N-acetylated COS mixture mainly contained glucosamine (GlcN) and some oligomers [(GlcN)n, n = 2-7]. The N-acetyl-D-glucosamine (GlcNAc) and peracetylated COSs [(GlcNAc)n, n = 2-7] were synthesised by treating the partially N-acetylated COS mixture with Ac2O-NaOAc. The peracetylated chitotetraose and chitopentaose were obtained by isolation of peracetylated COS mixture. NaOMe in dry MeOH was used for the deacetylation of peracetylated chitotetraose and chitopentaose, to give the tetra-N-acetyl- chitotetraose and penta-N-acetyl-chitopentaose, respectively.