27063-27-0 Usage
General Description
4-METHYL-2-QUINOLINAMINE, also known as 4-methyl-1,2-dihydroquinolin-2-imine, is a chemical compound with the molecular formula C10H10N2. It is a yellow to brown solid that is used as a building block in the synthesis of various pharmaceuticals and organic compounds. 4-METHYL-2-QUINOLINAMINE is a heterocyclic compound with a quinoline ring structure, and it has potential applications in the development of drugs for the treatment of various diseases. It is an important intermediate in the production of medicinal and agricultural chemicals and is also used in research and development in the pharmaceutical industry. However, it is important to handle this chemical with caution as it may pose health and safety hazards if not used properly.
Check Digit Verification of cas no
The CAS Registry Mumber 27063-27-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,0,6 and 3 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 27063-27:
(7*2)+(6*7)+(5*0)+(4*6)+(3*3)+(2*2)+(1*7)=100
100 % 10 = 0
So 27063-27-0 is a valid CAS Registry Number.
InChI:InChI=1/C10H10N2/c1-7-6-10(11)12-9-5-3-2-4-8(7)9/h2-6H,1H3,(H2,11,12)
27063-27-0Relevant articles and documents
Cu-catalyzed aerobic oxidative cyclizations of 3-N-hydroxyamino-1,2-propadienes with alcohols, thiols, and amines to form α-O-, S-, and N-substituted 4-methylquinoline derivatives
Sharma, Pankaj,Liu, Rai-Shung
supporting information, p. 4590 - 4594 (2015/03/18)
A one-pot, two-step synthesis of α-O-, S-, and Nsubstituted 4-methylquinoline derivatives through Cu-catalyzed aerobic oxidations of N-hydroxyaminoallenes with alcohols, thiols, and amines is described. This reaction sequence involves an initial oxidation of N-hydroxyaminoallenes with NuH (Nu = OH, OR, NHR, and SR) to form 3-substituted 2-en-1-ones, followed by Bronsted acid catalyzed intramolecular cyclizations of the resulting products. Our mechanistic analysis suggests that the reactions proceed through a radical-type mechanism rather than a typical ni-trone-intermediate route. The utility of this new Cu-catalyzed reaction is shown by its applicability to the synthesis of several 2-amino-4-methylquinoline derivatives, which are known to be key precursors to several bioactive molecules.
