27063-98-5

Basic information

• Product Name: 3-BROMO-4,5-DIMETHYLPYRIDINE
• Synonyms: 3-BROMO-4,5-DIMETHYLPYRIDINE
• CAS NO: 27063-98-5
• Molecular Formula: C7H8BrN
• Molecular Weight: 186.051
• Mol File: 27063-98-5.mol
• Article Data: 7

Chemical Properties

• Melting Point: 33-34 °C
• Boiling Point: 231.271°C at 760 mmHg
• Flash Point: 93.669°C
• Appearance: /
• Density: 1.416g/cm³
• Vapor Pressure: 0.095mmHg at 25°C
• Refractive Index: 1.547
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 3.82±0.28(Predicted)
• CAS DataBase Reference: 3-BROMO-4,5-DIMETHYLPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BROMO-4,5-DIMETHYLPYRIDINE(27063-98-5)
• EPA Substance Registry System: 3-BROMO-4,5-DIMETHYLPYRIDINE(27063-98-5)

Safety Data

• Hazardous Substances Data: 27063-98-5(Hazardous Substances Data)

Usage

General Description

3-Bromo-4,5-dimethylpyridine is a chemical compound with the molecular formula C7H8BrN. It is a substituted pyridine derivative that is commonly used in organic synthesis and pharmaceutical research. 3-BROMO-4,5-DIMETHYLPYRIDINE is a yellow-brown liquid at room temperature and is primarily used as a building block in the production of various pharmaceuticals, agrochemicals, and other organic compounds. It is known for its ability to undergo various chemical reactions, such as cross-coupling reactions using palladium catalysts, and is valued for its role in the development of new drugs and biologically active compounds. 3-Bromo-4,5-dimethylpyridine is considered to be a valuable intermediate in the field of chemical research and development.

InChI:InChI=1/C7H8BrN/c1-5-3-9-4-7(8)6(5)2/h3-4H,1-2H3

Upstream product

• 583-58-4 3,4-Lutidin 

Downstream Products

• 51454-50-3 3-bromo-5-methyl-pyridine-4-carbonitrile 
• 203569-15-7 3-bromo-4-formyl-5-methylpyridine 

Relevant articles and documents

A short synthesis of the plant alkaloid 4-methyl-2,6-naphthyridine

A new synthesis of the 2,6-naphthyridine alkaloid 4-methyl-2,6-naphthyridine from Antir-rhinum majus has been developed. Key steps are a regioselective oxidation of 3-bromo-4,5-dimethylpyridine to the corresponding 4-formyl derivative, and the annulation of the second pyridine ring by Suzuki-Miyaura cross-coupling using (E)-2-ethoxyvinylboronic acid pinacol ester as a masked acetaldehyde equivalent. This protocol gives the alkaloid in four steps starting from commercially available 3,4-dimethylpyridine in 15% overall yield. This annulation protocol should be useful for the synthesis of other condensed pyridines as well.

ALDOSTERONE SYNTHASE INHIBITORS

This invention relates to tricyclic triazole analogues of the formula I or their pharmaceutically acceptable salts, wherein the variable are defined herein. The inventive compounds selectively inhibit aldosterone synthetase. This invention also provides for pharmaceutical compositions comprising the compounds of Formula I or their salts as well as to methods for the treatment, amelioration or prevention of conditions that could be treated by inhibiting aldosterone synthetase.

ISOTHIAZOLOPYRIDIN-3-YLENAMINES FOR COMBATING ANIMAL PESTS

The present invention relates to lsothiazolopyridin-3-ylenamine compounds of the general formula I and to the agriculturally useful salts thereof and to compositions comprising such compounds. The invention also relates to the use of the lsothiazolopyridin-3-ylenamine compounds, of their salts or of compositions comprising them for combating animal pests. A lsothiazolopyridin-3-ylenamine compound of the present invention is represented by the following formula I: