27064-00-2

Basic information

• Product Name: 1-chloro-2-(2-nitrophenoxy)benzene
• Synonyms: 1-chloro-2-(2-nitrophenoxy)benzene
• CAS NO: 27064-00-2
• Molecular Formula: C₁₂H₈ClNO₃
• Molecular Weight: 249.64982
• EINECS: -0
• Mol File: 27064-00-2.mol
• Article Data: 9

Chemical Properties

• Melting Point: 48 °C
• Boiling Point: 209 °C(Press: 9 Torr)
• Appearance: /
• Density: 1.358±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 1-chloro-2-(2-nitrophenoxy)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-chloro-2-(2-nitrophenoxy)benzene(27064-00-2)
• EPA Substance Registry System: 1-chloro-2-(2-nitrophenoxy)benzene(27064-00-2)

Safety Data

• Hazardous Substances Data: 27064-00-2(Hazardous Substances Data)

Usage

Type of compound

Organic compound

Derivative

Chlorinated derivative of 2-(2-nitrophenoxy)benzene

Usage

Intermediate in the synthesis of other organic compounds

Physical form

Pale yellow solid

Molecular weight

247.65 g/mol

Natural occurrence

Not naturally occurring

Synthesis

Typically synthesized in a laboratory setting

Health and environment hazards

Considered hazardous to human health and the environment

Upstream product

• 95-57-8 2-monochlorophenol 
• 1493-27-2 ortho-nitrofluorobenzene 
• 17186-79-7 2-chlorophenyl methanesulfonate 
• 88-73-3 2-Chloronitrobenzene 

Downstream Products

• 860745-37-5 acetic acid-[2-(2-chloro-4-nitro-phenoxy)-4-nitro-anilide] 
• 873386-12-0 acetic acid-[2-(2-chloro-phenoxy)-4-nitro-anilide] 
• 873977-74-3 N -(2-(2-chlorophenoxy)phenyl)acetamide 
• 95-57-8 2-monochlorophenol 
• 2592-95-2 benzotriazol-1-ol 
• 135-67-1 phenoxazine 
• 859186-52-0 (2-chloro-4-nitro-phenyl)-(2-nitro-phenyl)-ether 
• 56966-47-3 2-(2-chlorophenoxy)aniline 

Relevant articles and documents

Microwave assisted rapid synthesis of phenoxazines and benzopyridoxazines

A facile protocol for the synthesis of phenoxazines and benzopyridoxazines by Smiles rearrangement have been demonstrated in short reaction time under microwave irradiation. The control experiments suggest that a reaction proceeds through Smiles rearrangement followed SNAr ring closure by in situ cascade process. In our present work, both the electron donating and electron withdrawing groups were tolerant and provided a corresponding phenoxazine/benzopyridoxazine in good to moderate yields.

Design, synthesis and antifungal activity of novel furancarboxamide derivatives

Twenty-seven novel furancarboxamide derivatives with a diphenyl ether moiety were synthesized and evaluated for their antifungal activity against Rhizoctonia solani, Botrytis cirerea, Valsa Mali and Sphaceloma ampelimum. Antifungal bioassay results indicated that most compounds had good or excellent fungicidal activities for R. solani and S. ampelimum at 20 mg L-1. Among synthesized compounds, compound 18e showed a greater inhibitory effect against S. ampelimum, with half maximal effective concentration (EC50) values of 0.020 mg L-1. This strong activity rivals currently used commercial fungicides, such as Boscalid and Carbendazim, and has great potential as a lead compound for future development of novel fungicides.

Synthesis and enantioselective hydrogenation of seven-membered cyclic imines: Substituted dibenzo[b,f][1,4]oxazepines

Highly enantioselective hydrogenation of seven-membered cyclic imines, substituted dibenzo[b,f][1,4]oxazepines, was achieved, with up to 94% ee, by using the [Ir(COD)Cl]2/(S)-Xyl-C3*-TunePhos complex as the catalyst in the presence of morpholine-HCl.