271769-95-0Relevant articles and documents
High stereochemical fidelity in reactions of an atropisomeric N- acyliminium intermediate
Godfrey, Christopher R. A.,Simpkins, Nigel S.,Walker, Matthew D.
, p. 388 - 390 (2007/10/03)
Atropisomeric lactams bearing a chiral auxiliary were prepared by condensation of L-menthol with N-ortho-tert-butylphenyl-5-hydroxypyrrolidin- 2-one. Substitution reactions of these compounds, via N-acyliminium intermediates, were demonstrated to be contr