271784-23-7

Basic information

• Product Name: 1-phenylsulfonyl-1H-pyrrolo[3,2-c]isoquinoline
• Synonyms: 1-phenylsulfonyl-1H-pyrrolo[3,2-c]isoquinoline
• CAS NO: 271784-23-7
• Molecular Weight: 308.36
• Mol File: 271784-23-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-phenylsulfonyl-1H-pyrrolo[3,2-c]isoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 1-phenylsulfonyl-1H-pyrrolo[3,2-c]isoquinoline(271784-23-7)
• EPA Substance Registry System: 1-phenylsulfonyl-1H-pyrrolo[3,2-c]isoquinoline(271784-23-7)

Safety Data

• Hazardous Substances Data: 271784-23-7(Hazardous Substances Data)

Upstream product

• 271784-16-8 4-amino-3-acetylenetrimethylsililisoquinoline 
• 40073-37-8 4-amino-3-bromoisoquinoline 
• 23687-25-4 4-aminoisoquinoline 
• 98-09-9 benzenesulfonyl chloride 
• 233-84-1 1H-pyrrolo[3,2-c]isoquinoline 

Relevant articles and documents

Synthesis of fused systems in the isoquinoline series: Oxazolo- and pyrrolo[3,2-c]isoquinolines

In order to synthesize the pyrrolo[3,2-c]isoquinoline structure, three different routes starting from readily available isoquinolines were tried. The ring closure reaction of a malonic derivative of 4-amino-3- bromoisoquinoline led to an oxazolo[3,2-c]isoquinoline instead of the target molecule. This latter was obtained via Sonagashira coupling reaction followed by ring closure under basic conditions. A study of the lithiation of the N- sulfonated pyrrolo[3,2-c]isoquinoline was undertaken. After optimization of the lithiation conditions, various 2-substituted pyrrolo[3,2-c]isoquinolines were obtained and their oxidation reactions studied.