2718-07-2Relevant articles and documents
Anticonvulsant activity of reaction products of 5,5-diphenylhydantoin with substituted methylene bromides
Usifoh, Cyril O.
, p. 366 - 368 (2001)
Some derivatives of 5,5-diphenylhydantoin (phenytoin) were synthesized by the alkylation of phenytoin with substituted methylene bromides. The hydantoins were evaluated for possible anticonvulsant activity in the maximal electroshock (MES)- and subcutaneous pentylenetetrazole (ScMet)-induced seizures and for neurotoxicity in the rotorod test in mice and rats.
Ligand-assisted click reaction for the synthesis of new hybrid compounds based on 1,2,3-triazoles and 5,5-diphenylimidazolidine-2,4-dione and evaluation of their antibacterial activities
Keivanloo, Ali,Lashkari, Saeed,Sepehri, Saghi,Bakherad, Mohammad,Abbaspour, Sima
, p. 935 - 943 (2020/05/29)
The new hybrid compounds based on 1,2,3-triazoles and 5,5-diphenylimidazolidine-2,4-dione were successfully synthesized by copper-catalyzed click reaction in the presence of water-soluble ligand, sodium 4-amino-5-hydroxy-7-sulfonaphthalene-2-sulfonate and