27185-57-5

Basic information

• Product Name: N,N'-(4-nitro-1,2-phenylene)bis(4-methylbenzenesulfonamide)
• Synonyms: N,N'-(4-nitro-1,2-phenylene)bis(4-methylbenzenesulfonamide)
• CAS NO: 27185-57-5
• Molecular Weight: 461.519
• Mol File: 27185-57-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N,N'-(4-nitro-1,2-phenylene)bis(4-methylbenzenesulfonamide)(CAS DataBase Reference)
• NIST Chemistry Reference: N,N'-(4-nitro-1,2-phenylene)bis(4-methylbenzenesulfonamide)(27185-57-5)
• EPA Substance Registry System: N,N'-(4-nitro-1,2-phenylene)bis(4-methylbenzenesulfonamide)(27185-57-5)

Safety Data

• Hazardous Substances Data: 27185-57-5(Hazardous Substances Data)

Upstream product

• 49633-28-5 1,2-bis-(p-methylphenylsulfonamido)-benzene 
• 98-59-9 p-toluenesulfonyl chloride 
• 99-56-9 4-Nitrophenylene-1,2-diamine 

Downstream Products

• 70376-36-2 5-nitro-1,3-bis-(toluene-4-sulfonyl)-1,3-dihydro-benzo[1,2,5]thiadiazole 2-oxide 

Relevant articles and documents

Pd(II)-Catalyzed Aerobic Intermolecular 1,2-Diamination of Conjugated Dienes: A Regio- and Chemoselective [4 + 2] Annulation for the Synthesis of Tetrahydroquinoxalines

A Pd(II)-catalyzed aerobic intermolecular 1,2-diamination of conjugated dienes was developed for the regio- and chemoselective preparation of a variety of functionalized tetrahydroquinoxalines, using simple sulfonyl protected o-phenylendiamines as a nitrogen source. This methodology provides a direct and efficient synthesis of tetrahydroquinoxalines. O2 was used as the stoichiometric oxidant, and reaction conditions were applied to a series of o-phenylendiamines and conjugated dienes. 35 examples are described, and good yields and selectivities are obtained for the majority of the products.

THE MENKE REACTION WITH DISULFONYL DERIVATIVES OF PHENYLENEDIAMINES

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