27223-35-4 Usage
Description
Ketazolam is a psychotropic benzodiazepine derivative characterized by its hypnotic and anxiolytic properties. It is a controlled substance that was used as an anxiolytic in the 1980s. However, its use is associated with tolerance development within fifteen days, physical dependence, and the potential for benzodiazepine withdrawal syndrome. Ketazolam is primarily intended for forensic purposes.
Uses
Used in Pharmaceutical Industry:
Ketazolam is used as a psychotropic medication for its anxiolytic and hypnotic effects. It is particularly beneficial in managing anxiety and insomnia, providing relief and promoting relaxation.
Used in Forensic Applications:
In the forensic field, ketazolam is utilized for its controlled substance status, aiding in the investigation and analysis of drug-related cases. Its psychotropic properties make it a relevant compound for understanding the effects of benzodiazepines on individuals and their potential involvement in criminal activities.
Originator
Anxon,Beecham,UK,1980
Manufacturing Process
A solution of 0.7 g of 2-(2-amino-N-methylacetamido)-5-chlorobenzophenone
in 10 ml of a 50% solution (by weight) of diketene in acetone is refluxed for 3
hours and then evaporated to give a brown oil. The oil is chromatographed on
200 g of silica gel using a 1:1 (by volume) mixture of ethyl acetate
cyclohexane; 25 ml fractions are collected. Fractions 11-14 are combined,
mixed with chloroform, evaporated and triturated with ether to give 0.337 g
of 11-chloro-8,12b-dihydro-2,8-dimethyl-12b-phenyl-4H-[1,3]oxazino[3,2-d]
[1.4] benzodiazepine-4,7(6H)-dione as a pale yellow solid, MP 174°C to
176°C.
Therapeutic Function
Antianxiety
Check Digit Verification of cas no
The CAS Registry Mumber 27223-35-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,2,2 and 3 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 27223-35:
(7*2)+(6*7)+(5*2)+(4*2)+(3*3)+(2*3)+(1*5)=94
94 % 10 = 4
So 27223-35-4 is a valid CAS Registry Number.
InChI:InChI=1/C20H17ClN2O3/c1-13-10-18(24)23-12-19(25)22(2)17-9-8-15(21)11-16(17)20(23,26-13)14-6-4-3-5-7-14/h3-11H,12H2,1-2H3
This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.