27239-48-1Relevant articles and documents
Oxime Ethers of (E)-11-Isonitrosostrychnine as Highly Potent Glycine Receptor Antagonists
Mohsen, Amal M. Y.,Mandour, Yasmine M.,Sarukhanyan, Edita,Breitinger, Ulrike,Villmann, Carmen,Banoub, Maha M.,Breitinger, Hans-Georg,Dandekar, Thomas,Holzgrabe, Ulrike,Sotriffer, Christoph,Jensen, Anders A.,Zlotos, Darius P.
, p. 2997 - 3005 (2016)
A series of (E)-11-isonitrosostrychnine oxime ethers, 2-aminostrychnine, (strychnine-2-yl)propionamide, 18-oxostrychnine, and N-propylstrychnine bromide were synthesized and evaluated pharmacologically at human α1 and α1β glycine receptors in a functional