272463-80-6Relevant articles and documents
Synthesis and evaluation of the antiproliferative activities of derivatives of carboxyalkyl isoflavones linked to N-t-Boc-hexylenediamine
Kohen, Fortune,Gayer, Batya,Kulik, Tikva,Frydman, Veronica,Nevo, Nava,Katzburg, Sara,Limor, Rona,Sharon, Orli,Stern, Naftali,Somjen, Dalia
, p. 6405 - 6410 (2007)
The isoflavones biochanin A (1a), genistein (1b), and daidzein (4) at concentrations >20 μM inhibit cell growth of various cancer cell lines. To enhance the antiproliferative activities of these compounds, we synthesized three analogs, 2-[3-carboxy-(6-ter
ISOFLAVONE DERIVATIVES AND USES THEREOF
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Page/Page column 25, (2008/12/08)
Isoflavone derivatives are provided comprising a carboxyalkylene moiety linked via its alkylene chain to the aromatic ring and via its carboxy group to an aminoalkyleneamino residue, which, in turn, is covalently linked to a functional group B. The isofla