27293-95-4

Basic information

• Product Name: 3-(4-chlorophenyl)-1,5-diphenyl-1H-pyrazole
• CAS NO: 27293-95-4
• Molecular Formula: C₂₁H₁₅ClN₂
• Molecular Weight: 330.8102
• Mol File: 27293-95-4.mol
• Article Data: 19

Chemical Properties

• Boiling Point: 500.2°C at 760 mmHg
• Flash Point: 256.3°C
• Density: 1.17g/cm³
• Vapor Pressure: 1.2E-09mmHg at 25°C
• Refractive Index: 1.635
• CAS DataBase Reference: 3-(4-chlorophenyl)-1,5-diphenyl-1H-pyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-chlorophenyl)-1,5-diphenyl-1H-pyrazole(27293-95-4)
• EPA Substance Registry System: 3-(4-chlorophenyl)-1,5-diphenyl-1H-pyrazole(27293-95-4)

Safety Data

• Hazardous Substances Data: 27293-95-4(Hazardous Substances Data)

Upstream product

• 10180-02-6 3-(4-chloro-phenyl)-1,5-diphenyl-4,5-dihydro-1H-pyrazole 
• 104-88-1 4-chlorobenzaldehyde 
• 536-74-3 phenylacetylene 
• 100-63-0 phenylhydrazine 
• 956-04-7 3-(4-chlorophenyl)-1-phenylprop-2-en-1-one 
• 59-88-1 phenylhydrazine hydrochloride 
• 956-02-5 4'-chlorochalcone 
• 100-52-7 benzaldehyde 
• 122-01-0 4-chloro-benzoyl chloride 
• 873-73-4 4-n-chlorophenylacetylene 
• 201230-82-2 carbon monoxide 
• 70-11-1 α-bromoacetophenone 
• 2829-26-7 N-(4-chlorobenzylidene)-N'-phenylhydrazine 
• 637-87-6 1-Chloro-4-iodobenzene 

Relevant articles and documents

TBHP/Cu(OAc)2 mediated oxidation of pyrazolines: A convenient method for the preparation of pyrazoles

An efficient and simple oxidative protocol has been developed for the preparation of pyrazoles from pyrazolines mediated by TBHP/Cu(OAc)2 at room temperature. The present protocol has been successfully applied for the preparation of various pyrazole compounds from heterocyclic pyrazolines.

Visible light mediated metal-free oxidative aromatization of 1,3,5-trisubstituted pyrazolines

The visible light mediated oxidation of 1,3,5-trisubstituted pyrazolines under metal-free conditions was developed. Various substituted pyrazolines were oxidized to pyrazoles by irradiation with visible light/sunlight. A plausible mechanism was proposed f

A Regioselective Approach to Trisubstituted Pyrazoles via Palladium-Catalyzed Oxidative Sonogashira-Carbonylation of Arylhydrazines

A palladium-catalyzed oxidative carbonylation of arylhydrazines and alkynes with balloon pressure CO/O2 to afford trisubstituted pyrazoles in a one-pot manner has been developed. The formation of trisubstituted pyrazoles involves a sequential C-N bond cleavage, carbonylation, Sonogashira coupling, Michael addition, and intramolecular condensation cyclization tandem process. An unprecedented oxidative Sonogashira-carbonylation reaction of arylhydrazine plays a key role for such a facile approach to pyrazoles.