273-70-1

Basic information

• Product Name: thiazolo[5,4-c]pyridine
• Synonyms: [1,3]Thiazolo[5,4-c]pyridine; Thiazolo[5,4-c]pyridine
• CAS NO: 273-70-1
• Molecular Formula: C₆H₄N₂S
• Molecular Weight: 136.17436
• Mol File: 273-70-1.mol
• Article Data: 7

Chemical Properties

• Melting Point: 105-108 °C(Solv: ethyl ether (60-29-7))
• Boiling Point: 264.282 °C at 760 mmHg
• Flash Point: 119.296 °C
• Appearance: /
• Density: 1.369 g/cm³
• Vapor Pressure: 0.016mmHg at 25°C
• Refractive Index: 1.705
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 2.33±0.40(Predicted)
• CAS DataBase Reference: thiazolo[5,4-c]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: thiazolo[5,4-c]pyridine(273-70-1)
• EPA Substance Registry System: thiazolo[5,4-c]pyridine(273-70-1)

Safety Data

• Hazardous Substances Data: 273-70-1(Hazardous Substances Data)

Usage

General Description

Thiazolo[5,4-c]pyridine is a heterocyclic compound containing a thiazole ring fused to a pyridine ring. It is used as a building block in the synthesis of various pharmaceutical and agrochemical compounds. Thiazolo[5,4-c]pyridine derivatives have been found to exhibit a wide range of biological activities, including anticancer, antifungal, and antibacterial properties. Furthermore, they have also shown potential as inhibitors of certain enzymes and receptors, making them valuable in drug discovery and development. The unique structure and diverse biological activities of thiazolo[5,4-c]pyridine make it an important chemical in the field of medicinal chemistry and chemical biology.

InChI:InChI=1/C6H4N2S/c1-2-7-3-6-5(1)8-4-9-6/h1-4H

Upstream product

• 52334-54-0 4-aminopyridine-3-thiol 
• 64-18-6 formic acid 
• 129333-20-6 <4-<(2,2-dimethyl-1-oxopropyl)amino>-3-pyridinyl>diethylcarbamodithioate 
• 365996-04-9 4-[(tert-Butoxycarbonyl)amino]-3-mercaptopyridine 
• 100724-20-7 (3-mercapto-[4]pyridyl)-carbamic acid benzyl ester 
• 98400-69-2 N-(4-pyridyl) t-butyl carbamate 
• 70298-89-4 4-N-pivaloylaminopyridine 
• 129333-22-8 <4-(acetylamino)-3-pyridinyl>diethylcarbamodithioate 
• 129333-21-7 <4-amino-3-pyridinyl>diethylcarbamodithioate 
• 98383-10-9 2-methylthiazolo[5,4-c]pyridine 

Downstream Products

• 108310-79-8 thiazolo[5,4-c]pyridin-2-ylamine 

Relevant articles and documents

Diamine derivatives

A compound represented by the general formula (1): Q1-Q2-T0-N(R1)-Q3-N(R2)-T1-Q4??(1) wherein R1 and R2 are hydrogen atoms or the like; Q1 is a saturated or unsaturated, 5- or 6-membered cyclic hydrocarbon group which may be substituted, or the like; Q2 is a single bond or the like; Q3 is a group in which Q5 is an alkylene group having 1 to 8 carbon atoms, or the like; and T0 and T1 are carbonyl groups or the like; a salt thereof, a solvate thereof, or an N-oxide thereof. The compound is useful as an agent for preventing and/or treating cerebral infarction, cerebral embolism, myocardial infarction, angina pectoris, pulmonary infarction, pulmonary embolism, Buerger's disease, deep venous thrombosis, disseminated intravascular coagulation syndrome, thrombus formation after valve or joint replacement, thrombus formation and reocclusion after angioplasty, systemic inflammatory response syndrome (SIRS), multiple organ dysfunction syndrome (MODS), thrombus formation during extracorporeal circulation, or blood clotting upon blood drawing.

DIAMINE DERIVATIVES

A compound represented by formula (1):Q1-Q2-To-N(R1) -Q3-N(R2)-T1-Q4 [wherein R1 and R2 are hydrogen atoms or the like; Q1 is a saturated or unsaturated, 5- or 6- membered cyclic hydrocarbon group which may be substituted, or the like; Q2 is a single bond or the like; Q3 represents the following group: (wherein Q5 is an alkylene group having 1 to 8 carbon atoms, or the like); and T0 and T1 are carbonyl groups or the like], a salt thereof, a solvate thereof, or an N-oxide thereof. The compound is useful as an agent for preventing and/or treating cerebral infarction, cerebral embolism, myocardial infarction, angina pectoris, pulmonary infarction, pulmonary embolism, Buerger's disease, deep venous thrombosis, disseminated intravascular coagulation syndrome, thrombus formation after artificial valve or joint replacement, thrombus formation and reocclusion after angioplasty, systemic inflammatory response syndrome (SIRS), multiple organ dysfunction syndrome (MODS), thrombus formation during extracorporeal circulation, or blood clotting upon blood drawing.

DIAMINE DERIVATIVES

A compound represented by the general formula (1):Q1-Q2-T0-N(R1)-Q3-N(R2)-T1-Q4 wherein R1 and R2 are hydrogen atoms or the like; Q1 is a saturated or unsaturated, 5- or 6- membered cyclic hydrocarbon group which may be substituted, or the like; Q2 is a single bond or the like; Q3 is a group in which Q5 is an alkylene group having 1 to 8 carbon atoms, or the like; and T0 and T1 are carbonyl groups or the like; a salt thereof, a solvate thereof, or an N-oxide thereof. The compound is useful as an agent for preventing and/or treating cerebral infarction, cerebral embolism, myocardial infarction, angina pectoris, pulmonary infarction, pulmonary embolism, Buerger's disease, deep venous thrombosis, disseminated intravascular coagulation syndrome, thrombus formation after valve or joint replacement, thrombus formation and reocclusion after angioplasty, systemic inflammatory response syndrome (SIRS), multiple organ dysfunction syndrome (MODS), thrombus formation during extracorporeal circulation, or blood clotting upon blood drawing.