27311-63-3Relevant articles and documents
PIFA-Mediated Cross-Dehydrogenative Coupling of N-Heteroarenes with Cyclic Ethers: Ethanol as an Efficient Promoter
Li, Xiang,Liu, Chaoyang,Guo, Shixun,Wang, Wei,Zhang, Yongqiang
, p. 411 - 421 (2021)
Ethanol is typically used in organic synthesis as an environmentally benign solvent. Herein, we report a mild and efficient cross-dehydrogenative coupling (CDC) reaction of N-heteroarenes with cyclic ethers by uncovering the new reactivity of ethanol as an efficient promoter in PIFA-mediated radical process. The reaction proceeds smoothly under the irradiation of visible light and features excellent functional group compatibility, which allows the expedite synthesis of a variety of medicinally valuable Cα-heteroarylated cyclic ethers in moderate to high yields.
Stereospecific synthesis of a 1β-methylcarbapenem intermediate
Oda, Kozo,Nishi, Takahide
, p. 446 - 448 (1997)
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Heteroarylation of Ethers, Amides, and Alcohols with Light and O2
Bhakat, Manotosh,Biswas, Promita,Dey, Jayanta,Guin, Joyram
supporting information, p. 6886 - 6890 (2021/09/14)
An efficient protocol for the Cα-H heteroarylation of ethers, amides, and alcohols using air and light under mild conditions is described. The reaction is applicable to a wide spectrum of functional groups. The generation of C-radicals via photoinduced aerobic oxidation of ethers, amides, and alcohols is the key feature of the process. Control experiments suggest a radical pathway for the reaction.