27318-90-7 Usage
Description
1,10-Phenanthroline-5,6-dione (phendio) is a bifunctional quinone oxidant that forms Cu(II) and Ag(I) phendio complexes, exhibiting potent anti-fungal and anti-cancer activity. It is a yellow solid and has the ability to catalyze the aerobic oxidation of secondary amines to various value-added motifs, including indoles, when used in conjunction with Zn2+ catalysts. The modification of glassy carbon (GC) electrodes with phendio complexes of transition metals also leads to the catalytic oxidation of NADH at low overpotential.
Uses
Used in Chemical Synthesis:
1,10-Phenanthroline-5,6-dione is used as a bifunctional quinone oxidant for the aerobic oxidation of secondary amines to a variety of value-added motifs, including indoles. This application is particularly useful in the synthesis of complex organic compounds and pharmaceuticals.
Used in Antifungal Applications:
1,10-Phenanthroline-5,6-dione is used as an antifungal agent due to its ability to form Cu(II) and Ag(I) phendio complexes, which show potent anti-fungal activity. This makes it a valuable compound in the development of new antifungal drugs and treatments.
Used in Anticancer Applications:
1,10-Phenanthroline-5,6-dione is used as an anticancer agent, as its Cu(II) and Ag(I) phendio complexes exhibit potent anti-cancer activity. These complexes can be employed in the development of new cancer treatments and therapies.
Used in Electrochemistry:
1,10-Phenanthroline-5,6-dione is used in the modification of glassy carbon (GC) electrodes to form phendio complexes of transition metals. This application is utilized for the catalytic oxidation of NADH at low overpotential, making it a valuable compound in the field of electrochemistry and sensor development.
Used in Pharmaceutical Industry:
1,10-Phenanthroline-5,6-dione is used as a key compound in the development of new drugs and therapies, particularly in the areas of antifungal and anticancer applications. Its unique properties and ability to form complexes with various metals make it a promising candidate for pharmaceutical research and development.
Used in Material Science:
1,10-Phenanthroline-5,6-dione is used in the modification of glassy carbon (GC) electrodes, which can lead to the development of new materials with enhanced electrochemical properties. This application is particularly relevant in the field of sensor technology and energy storage devices.
Check Digit Verification of cas no
The CAS Registry Mumber 27318-90-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,3,1 and 8 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 27318-90:
(7*2)+(6*7)+(5*3)+(4*1)+(3*8)+(2*9)+(1*0)=117
117 % 10 = 7
So 27318-90-7 is a valid CAS Registry Number.
InChI:InChI=1/C12H6N2O2/c15-11-7-3-1-5-13-9(7)10-8(12(11)16)4-2-6-14-10/h1-6H
27318-90-7Relevant articles and documents
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Smith,Cagle
, p. 781,782 (1947)
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Eu-MOFs with 2-(4-carboxyphenyl)imidazo[4,5-f]-1,10-phenanthrolineand ditopic carboxylates as coligands: Synthesis, structure, high thermostability, and luminescence properties
Zhang, Sheng,Yang, Yang,Xia, Zheng-Qiang,Liu, Xiang-Yu,Yang, Qi,Wei, Qing,Xie, Gang,Chen, San-Ping,Gao, Sheng-Li
, p. 10952 - 10963 (2014)
(Graph Presented) Hydrothermal reactions of europium(III) salt with 2-(4-carboxyphenyl)imidazo[4,5- f ]-1,10-phenanthroline and dicarboxylic acid as coligands - benzene-1,4-dicarboxylic acid, 4,4′-biphenyldicarboxylic acid, 2,5-dibromoterephthalic acid, and naphthalene-1,4-dicarboxylic acid - lead to four europium fluorescent materials (1-4). Structural analyses reveal that 1 - 4 have binuclear 3D metal - organic frameworks with different channels, void volumes, and conjugated structures tuned by ditopic carboxylates. There are no latticed and coordinated water molecules occurring in 1 - 3, while the free water molecules fill in 1D channels of 4. 4′ was readily obtained via water removal of 4. Thermal analyses of all compounds show the high thermal stability of the main framework up to 450 °C. Optical studies indicate that 1 - 4 and 4′ show the characteristic red luminescence emission of the EuIII ion in the visible regions at room temperature. On the basis of emission spectra, their luminescence lifetimes were determined. In particular, compound 4??? shows a longer lifetime (τ = 0.942 ms) and significantly enhanced quantum yield (39%) compared with those of 1 (11%, 0.770 ms), 2 (4%, 0.414 ms), 3 (18%, 0.807 ms), and 4 (26%, 0.858 ms).
Hydrothermal syntheses, crystal structures, and photophysical properties of two coordination polymers with mixed ligands
Yan, Li,Liu, Chun-Ling
, p. 119 - 125 (2017)
Two novel metal-organic coordination polymers [Cd(ipdt)(m-BDC)·3H2O]n (1) and [Pb(mip)2(NTC) ·2H2O]n (2) [ipdt = 2,6-Dimethoxy-4-(1H-1,3,7,8-tetraaza-cyclopenta[l]phenanthren-2-yl)-phenol, mip = 2-(3-
COMPLEX COMPRISING A RARE-EARTH METAL ION AND A COMPLEXING MOIETY
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Page/Page column 4; 11, (2010/11/29)
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