27330-57-0

Basic information

• Product Name: Benzoic acid, 3-(1,1-dimethylethyl)-, methyl ester
• Synonyms: m-tert.-Butylbenzoesaeuremethylester;m-Carbomethoxy-tert.-butylbenzol;Benzoic acid,3-(1,1-dimethylethyl)-,methyl ester
• CAS NO: 27330-57-0
• Molecular Formula: C12H16O2
• Molecular Weight: 192.258
• Mol File: 27330-57-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 3-(1,1-dimethylethyl)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 3-(1,1-dimethylethyl)-, methyl ester(27330-57-0)
• EPA Substance Registry System: Benzoic acid, 3-(1,1-dimethylethyl)-, methyl ester(27330-57-0)

Safety Data

• Hazardous Substances Data: 27330-57-0(Hazardous Substances Data)

Upstream product

• 186581-53-3 diazomethane 
• 253185-03-4 tert-butylbenzene 
• 124-38-9 carbon dioxide 
• 507-19-7 t-butyl bromide 
• 618-89-3 methyl 3-bromobenzoate 
• 585-34-2 3-tert-butylphenyol 
• 67-56-1 methanol 
• 201230-82-2 carbon monoxide 
• 201851-06-1 m-(tert-butyl)phenyl trifluoromethanesulfonate 
• 21900-36-7 3-(tert-butyl)benzoyl chloride 
• 124-41-4 sodium methylate 
• 57031-51-3 Methyl-tert.-butylperoxyoxalat 

Downstream Products

• 1334336-44-5 C₃₅H₅₂O₂Si 
• 1215115-65-3 (17β)-17-(3-tert-butylbenzyl)-estra-1(10),2,4-triene-3,17-diol 
• 51503-09-4 3-tert-butylbenzyl alcohol 
• 102405-32-3 3-tert-butylbenzyl bromide 
• 67-56-1 methanol 
• 7498-54-6 3-t-Butylbenzoic acid 

Relevant articles and documents

Nickel-Catalyzed Reductive Coupling of Aryl Bromides with Tertiary Alkyl Halides

A mild Ni-catalyzed reductive arylation of tertiary alkyl halides with aryl bromides has been developed that delivers products bearing all-carbon quaternary centers in moderate to excellent yields with excellent functional group tolerance. Electron-deficient arenes are generally more effective in inhibiting alkyl isomerization. The reactions proceed successfully with pyridine or 4-(dimethylamino)pyridine, while imidazolium salts slightly enhance the coupling efficiency.

Dimetalation: The acidity of monometalated arenes towards superbasic reagents

Twofold hydrogen/metal interconversions ("dimetalations") can be accomplished with "spiny" arenes (tert-butylbenzene, 1,4-di-tert-butylbenzene, 1,1,3,3-tetramethylindane and congeners) and N,N-crowded anilines (2,2,6,6-tetramethyl-1-phenylpiperidine and N

Carbonylation of Organomercury Compounds: A General Synthesis of Carboxylic Acids and Esters

Organomercury compounds react with carbon monoxide in aqueous or alcoholic media to give good yields of carboxylic acids or esters.The carboxyl group is introduced selectively at the site of the carbon-mercury bond.Homogeneous group 9 and 10 metal complexes catalyze this carbonylation reaction, which yields mercury(0) as the inorganic byproduct.The mercuration-carbonylation sequence represents a general synthesis of carboxylic acids and esters.