27334-45-8

Basic information

• Product Name: Benzoic acid, 2-(1,1-dimethylethyl)-, methyl ester
• CAS NO: 27334-45-8
• Molecular Formula: C12H16O2
• Molecular Weight: 192.258
• Mol File: 27334-45-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2-(1,1-dimethylethyl)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-(1,1-dimethylethyl)-, methyl ester(27334-45-8)
• EPA Substance Registry System: Benzoic acid, 2-(1,1-dimethylethyl)-, methyl ester(27334-45-8)

Safety Data

• Hazardous Substances Data: 27334-45-8(Hazardous Substances Data)

Upstream product

• 507-19-7 t-butyl bromide 
• 610-94-6 2-bromobenzoic acid methyl ester 
• 7073-99-6 2-tert-butylbromobenzene 
• 186581-53-3 diazomethane 
• 1077-58-3 2-tert-butylbenzoic acid 

Downstream Products

• 22583-61-5 1-(2-tert-butylphenyl)ethan-1-one 
• 27330-55-8 Methyl 6-tert.-butyl-1-cyclohexen-1-carboxylat 
• 21190-35-2 (tert-butylphenyl)methyl alcohol 

Relevant articles and documents

Nickel-Catalyzed Reductive Coupling of Aryl Bromides with Tertiary Alkyl Halides

A mild Ni-catalyzed reductive arylation of tertiary alkyl halides with aryl bromides has been developed that delivers products bearing all-carbon quaternary centers in moderate to excellent yields with excellent functional group tolerance. Electron-deficient arenes are generally more effective in inhibiting alkyl isomerization. The reactions proceed successfully with pyridine or 4-(dimethylamino)pyridine, while imidazolium salts slightly enhance the coupling efficiency.