273737-39-6Relevant articles and documents
Design of small molecules that recognize RNA: Development of aminoglycosides as potential antitumor agents that target oncogenic RNA sequences
Sucheck, Steven J.,Greenberg, William A.,Tolbert, Thomas J.,Wong, Chi-Huey
, p. 1080 - 1084 (2007/10/03)
Functional single-stranded oncogenic mRNAs such as the breakpoints of the PAX3-FKHR and Bcr-Abl oncogenes bind selectively and with high affinity to naturally occurring, as well as synthetic, aminoglycosides. The latter, neamine-derived compounds were des