27409-30-9 Usage
Description
Picroside I is an iridoid glycoside found in Picroliv, a hepatoprotective mixture of compounds isolated from an herb native to the Himalayas. It possesses various biological activities, including anti-inflammatory, hepatoprotective, and neurite outgrowth-promoting properties.
Uses
Used in Pharmaceutical Industry:
Picroside I is used as an anti-inflammatory agent for its ability to act as an oxygen free radical scavenger, promoting anti-inflammatory activity and potentially being used in the treatment of arthritis.
Used in Hepatoprotection:
Picroside I is used as a hepatoprotective agent for its ability to block changes in acid phosphatase activity, phospholipid levels, and lipid peroxide production induced by D-galactosamine in rat liver, thus protecting the liver from damage.
Used in Neurological Applications:
Picroside I is used as a neurite outgrowth-promoting agent for its ability to enhance neurite outgrowth in PC12D cells induced by basic fibroblast growth factor and 7S nerve growth factor when given at 60 μM, potentially benefiting neurological treatments and therapies.
Used in Drug Resistance:
Picroside I is used to enhance the ATPase activity of the efflux transporter P-glycoprotein at concentrations as low as 5 μM, which may help in overcoming drug resistance in cancer treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 27409-30-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,4,0 and 9 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 27409-30:
(7*2)+(6*7)+(5*4)+(4*0)+(3*9)+(2*3)+(1*0)=109
109 % 10 = 9
So 27409-30-9 is a valid CAS Registry Number.
InChI:InChI=1/C24H28O11/c25-11-24-16-13(17(27)21(24)35-24)8-9-31-22(16)34-23-20(30)19(29)18(28)14(33-23)10-32-15(26)7-6-12-4-2-1-3-5-12/h1-9,13-14,16-23,25,27-30H,10-11H2/b7-6+/t13-,14-,16-,17+,18-,19+,20-,21+,22+,23+,24-/m1/s1