2759-54-8

Basic information

• Product Name: 4-chloropropionanilide
• Synonyms: 4-chloropropionanilide
• CAS NO: 2759-54-8
• Molecular Formula: C₉H₁₀ClNO
• Molecular Weight: 183.6348
• Mol File: 2759-54-8.mol
• Article Data: 21

Chemical Properties

• Melting Point: 137-139 °C
• Boiling Point: 344.2°Cat760mmHg
• Flash Point: 162°C
• Appearance: /
• Density: 1.216g/cm³
• Vapor Pressure: 6.67E-05mmHg at 25°C
• Refractive Index: 1.577
• PKA: 14.25±0.70(Predicted)
• CAS DataBase Reference: 4-chloropropionanilide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloropropionanilide(2759-54-8)
• EPA Substance Registry System: 4-chloropropionanilide(2759-54-8)

Safety Data

• Hazardous Substances Data: 2759-54-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H10ClNO/c1-2-9(12)11-8-5-3-7(10)4-6-8/h3-6H,2H2,1H3,(H,11,12)

Upstream product

• 620-71-3 N-(phenyl)-2-methylacetamide 
• 64-19-7 acetic acid 
• 940-36-3 (4-chloro-phenyl)-carbamic acid methyl ester 
• 97-93-8 triethylaluminum 
• 106-47-8 4-chloro-aniline 
• 56962-09-5 1-(4-chlorophenyl)-N-hydroxypropan-1-imine 
• 79-03-8 propionyl chloride 
• 637-87-6 1-Chloro-4-iodobenzene 
• 79-05-0 Propionamid 
• 802294-64-0 propionic acid 
• 100-00-5 4-chlorobenzonitrile 
• 123-62-6 propionic acid anhydride 

Downstream Products

• 1685-20-7 1-(2-amino-5-chlorophenyl)propan-1-one 
• 25428-06-2 2-amino-5-methyl-acetophenone 
• 73938-86-0 p-chloro-N-(n-propyl)aniline 
• 1638490-79-5 1-(4-chlorophenyl)-4-phenylquinolin-2(1H)-one 
• 709-98-8 Propanil 
• 1027019-12-0 6-chloro-2-ethylbenzo[d]oxazole 
• 35274-18-1 4'-chlorothiopropionanilide 
• 642410-38-6 2-bromo-N-(4-chlorophenyl)-N-propylacetamide 
• 17142-83-5 6-chloro-2-ethylbenzo[d]thiazole 

Related news

ω-And (ω-1)-hydroxylation of 4-chloropropionanilide (cas 2759-54-8) in liver microsomes of rabbits treated with phenobarbital or 3-methylcholanthrene07/16/2019

Hydroxylation of 4-chloropropionanilide to 4-chlorohydracrylanilide, ω-hydroxylation, and to 4-chlorolactanilide, (ω-1)-hydroxylation, by rabbit liver microsomes were found to be stimulated differently by treatment of rabbits with phenobarbital or 3-methylcholanthrene. ω-Hydroxylation was not...detailed

ω-And (ω-1)-hydroxylation of 4-chloropropionanilide (cas 2759-54-8) by rabbits and rabbit liver microsomes07/15/2019

4-Chlorolactanilide, 4-chlorohydracrylanilide, 4-chloroglyceranilide, and 4-chloroglycolanilide were isolated from urine of rabbits injected with 4-chloropropionanilide. The product of (ω-1)-hydroxylation amounted to nearly 30 per cent of the dose and the ω-OH derivative to about 4 per cent. A...detailed

Relevant articles and documents

Thermal behaviors of ionic liquids under microwave irradiation and their application on microwave-assisted catalytic Beckmann rearrangement of ketoximes

Microwave-assisted Beckmann rearrangements of ketoximes in room temperature ionic liquids have been accomplished successfully using only 5 mol% of H2SO4 as a catalyst.

Cu-Mediated Synthesis of Indolines and Dihydroisoquinolinones through Arylperfluoroalkylation of Unactivated Alkenes

The copper-mediated fluroalkylation/cyclization of N-allyl anilines has been described using fluoroalkyl iodides as fluoroalkylation reagents for the first time. The reaction provides an efficient and direct access to 3-fluoroalkyl indolines in moderate to good yields with unactivated double bonds as the radical acceptor. This protocol combines a simple experimental procedure with low-costing fluoroalkylated sources and excellent functional group tolerance.

Palladium(II)-Catalyzed Oxidative Homo- and Cross-Coupling of Aryl ortho -sp2 C-H Bonds of Anilides at Room Temperature

The preparation of secondary 2,2'-bisanilides has been successfully achieved through an oxidative coupling of aryl ortho-sp2 C-H bonds of anilides in the presence of catalytic Pd(OAc)2 and K2S2O8 as an oxidant in MsOH/CF3CO2H (TFA) at room temperature (25 °C). The aromatic rings of anilides substituted by various electron-donating or electron-withdrawing groups are tolerant in these coupling reactions.