276695-20-6

Basic information

• Product Name: 3-Carbobenzyloxy-8,9-Difluoro-2,3,4,4a-Tetrahydro-1H-Pyrazino[1,2-a]-Quinoxalin-5(6H)-One
• CAS NO: 276695-20-6
• Molecular Weight: 373.359
• Mol File: 276695-20-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-Carbobenzyloxy-8,9-Difluoro-2,3,4,4a-Tetrahydro-1H-Pyrazino[1,2-a]-Quinoxalin-5(6H)-One(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Carbobenzyloxy-8,9-Difluoro-2,3,4,4a-Tetrahydro-1H-Pyrazino[1,2-a]-Quinoxalin-5(6H)-One(276695-20-6)
• EPA Substance Registry System: 3-Carbobenzyloxy-8,9-Difluoro-2,3,4,4a-Tetrahydro-1H-Pyrazino[1,2-a]-Quinoxalin-5(6H)-One(276695-20-6)

Safety Data

• Hazardous Substances Data: 276695-20-6(Hazardous Substances Data)

Upstream product

• 276695-19-3 4-carbobenzyloxy-1-(4,5-difluoro-2-nitrophenyl)-piperazine-2-carboxylic acid 
• 934630-06-5 4-(benzyloxy-carbonyl)-2-piperazinecarboxylic acid 

Downstream Products

• 73187-21-0 2,3,4,4a,5,6-Hexahydro-1(H)-pyrazino<1,2-a>chinoxalin 

Relevant articles and documents

2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)one derivatives

This invention provides compounds of formula I, wherein R is hydrogen or alkyl of 1-6 carbon atoms; R′ is hydrogen, alkyl of 1-6 carbon atoms, acyl of 2-7 carbon atoms, or aroyl; R1, R2, R3, and R4are each, inde

Synthesis and 5-hydroxytryptamine (5-HT) activity of 2,3,4,4a-Tetrahydro-1H-pyrazino[1,2-a]quinozalin-5-(6H)ones and 2,3,4,4a,5,6-hexahydro-1H-pyrazino [1,2-,a] quinoxalines

A series of 2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5-(6H)ones and 2,3,4,4a,5,6-hexahydro- 1H-pyrazino[1,2-a]-quinoxalines was shown to exhibit 5-HT(2C) agonist binding and functional activity. Compound 21R inhibited food intake over 2 h in fasted, male Sprague-Dawley rats with ED50 values of 2 mg/kg (ip) and 10 mg/kg (po). (C) 2000 Elsevier Science Ltd.