276697-76-8

Basic information

• Product Name: 1-(Allyloxy)-2-(trifluoromethoxy)benzene
• Synonyms: 1-(Allyloxy)-2-(trifluoromethoxy)benzene
• CAS NO: 276697-76-8
• Molecular Formula: C₁₀H₉F₃O₂
• Molecular Weight: 218.17
• Mol File: 276697-76-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 194.6±35.0 °C(Predicted)
• Appearance: /
• Density: 1.199±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 1-(Allyloxy)-2-(trifluoromethoxy)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(Allyloxy)-2-(trifluoromethoxy)benzene(276697-76-8)
• EPA Substance Registry System: 1-(Allyloxy)-2-(trifluoromethoxy)benzene(276697-76-8)

Safety Data

• Hazardous Substances Data: 276697-76-8(Hazardous Substances Data)

Usage

Type of compound

Aromatic ether

Structural features

Contains an allyl group
Contains a trifluoromethoxy group
Attached to a benzene ring

Common uses

Synthesis of pharmaceuticals
Synthesis of agrochemicals
Synthesis of other organic compounds

Potential applications

Material science
Building block for new chemical compounds

Additional uses

Organic electronics
Precursor for advanced materials with specific properties

Importance

Wide range of potential applications and an important building block in organic chemistry.

Upstream product

• 1006904-72-8 silver(I) trifluoromethoxide 
• 25125-40-0 1-(2-(allyloxy)phenyl)-2-(tetrafluoro-λ⁵-boraneyl)diazene 
• 32858-93-8 2-(trifluoromethoxy)phenol 
• 106-95-6 allyl bromide 

Downstream Products

• 276697-77-9 O-CF₃-O'-3-hydroxy-n-propyl-catechol 
• 709630-93-3 (R)-3-Hydroxy-2-(4-methoxy-3-propyl-5-trifluoromethoxy-benzoylamino)-propionic acid methyl ester 
• 445018-78-0 2-(4-methoxy-3-propyl-5-trifluoromethoxyphenyl)-4,5-dihydrooxazole-4-catboxylic acid methyl ester 
• 445018-77-9 4-methoxy-5-propyl-3-trifluoromethoxybenzoic acid 
• 709619-79-4 5-bromo-2-methoxy-1-propyl-3-trifluoromethoxy-benzene 
• 709614-51-7 4-bromo-2-propyl-6-trifluoromethoxy-phenol 
• 445018-76-8 6-propyl-2-trifluomethoxyphenol 
• 1026470-39-2 2-allyl-6-trifluoromethoxy-phenol 

Relevant articles and documents

Silver-Mediated Trifluoromethoxylation of (Hetero)aryldiazonium Tetrafluoroborates

Here we report a silver-mediated trifluoromethoxylation of (hetero)aryldiazonium tetrafluoroborates by converting an aromatic amino group into an OCF3 group. This method, which can be considered to be a trifluoromethoxylation variation of the classic Sandmeyer-type reaction, uses readily available aryl and heteroaromatic amines as starting materials and AgOCF3 as trifluoromethoxylating reagents. The broad substrate scope and simple, mild reaction condition made this transformation a valuable method in constructing aryl-OCF3 bonds.

NEW AMIDINO DERIVATIVES AND THEIR USE AS THROMBIN INHIBITORS

There is provided compounds of formula Iwherein R, Rx, Y, R, n and B have meanings given in the description which are useful as competitive inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions wher