2772-46-5

Basic information

• Product Name: 4,5-DICHLOROVERATROL
• Synonyms: 4,5-DICHLOROVERATROL;4,5-DICHLOROVERATROLE;1,2-Dichloro-4,5-dimethoxybenzene;1,2-Dimethoxy-4,5-dichloro-benzene;Benzene, 4,5-dichloro-1,2-dimethoxy;4,5-Dichloro-1,2-dimethoxybenzene
• CAS NO: 2772-46-5
• Molecular Formula: C₈H₈Cl₂O₂
• Molecular Weight: 207.05
• Mol File: 2772-46-5.mol
• Article Data: 5

Chemical Properties

• Melting Point: 83°C
• Boiling Point: 297.35°C (rough estimate)
• Flash Point: 98.8 °C
• Appearance: /
• Density: 1.3354 (rough estimate)
• Vapor Pressure: 0.0239mmHg at 25°C
• Refractive Index: 1.5537 (estimate)
• Storage Temp.: -20°C, Inert atmosphere
• Solubility: Chloroform (Slightly), Methanol (Slightly, Heated)
• Water Solubility: 72.3mg/L(25 oC)
• CAS DataBase Reference: 4,5-DICHLOROVERATROL(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-DICHLOROVERATROL(2772-46-5)
• EPA Substance Registry System: 4,5-DICHLOROVERATROL(2772-46-5)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 2772-46-5(Hazardous Substances Data)

Usage

General Description

4,5-Dichloroveratrol is a synthetic chemical compound that belongs to the family of stilbenes, which are unsaturated hydrocarbons. 4,5-DICHLOROVERATROL contains two phenol functional groups adjacent to an ethene double bond, which is the defining characteristic of stilbenes. It also features two chlorine atoms, which distinguishes it from the veratrol molecule. However, there is limited information available on its specific properties or potential applications. Its toxicity, pharmaceutical relevance, and environmental impact have not been extensively researched, thus the possible uses and effects of 4,5-dichloroveratrol remain largely unknown.

InChI:InChI=1/C8H8Cl2O2/c1-11-7-3-5(9)6(10)4-8(7)12-2/h3-4H,1-2H3

Upstream product

• 186581-53-3 diazomethane 
• 2460-49-3 4,5-dichloroguaiacol 
• 90-05-1 2-methoxy-phenol 
• 17078-88-5 1-(3,4-dimethoxyphenyl)-2-(2-methoxyphenoxy)ethanol 
• 3428-24-8 4,5-dichlorocatechol 
• 74-88-4 methyl iodide 
• 91-16-7 1,2-dimethoxybenzene 

Downstream Products

• 101252-15-7 2,3-dichloro-5,6-dimethoxy-aniline 
• 175883-58-6 Trifluoro-methanesulfonic acid 4,5-dichloro-2-trifluoromethanesulfonyloxy-phenyl ester 
• 126840-15-1 [3,4,5,6-²H₄]-1,2-dimethoxybenzene 
• 113440-41-8 C₈H₆⁽²⁾H₂Cl₂O₂ 
• 91-16-7 1,2-dimethoxybenzene 
• 16766-27-1 4-chloro-1,2-dimethoxybenzene 
• 24605-23-0 2-chloro-5-methoxybenzoquinone 
• 117882-84-5 1,2-dichloro-4,5-dimethoxy-3-nitro-benzene 
• 1128-57-0 1,2-dimethoxy-4,5-dimethylbenzene 
• 3428-24-8 4,5-dichlorocatechol 

Relevant articles and documents

-

-

The kinetics of lignin reactions during chlorine dioxide bleaching. Part 1. Influence of pH and temperature on the reaction of 1-(3,4-dimethoxyphenyl)ethanol with chlorine dioxide in aqueous solution

Rate constants as well as the products formed from the reaction between chlorine dioxide and the non-phenolic lignin model compound 1-(3,4-dimethoxyphenyl)ethanol have been determined in the pH interval 3-8. Spectroscopic data for the substrate and some products are given. The pH of the reaction mixture has a large influence on both the rate constant and the product distribution. Under technical chlorine dioxide bleaching conditions (pH 3, 40°C and an ionic strength of 0.3 mol kg-1 ) the rate constant has been found to be 0.12(2) M-1 s-1, which corresponds to a half-life of approximately 7 min in 0.01 M solution. The influence of temperature [Ea = 29(7)kJ mol-1] on the rate of reaction of this lignin model is small. At acidic pH (35) a large variety of both oxidized (quinones, lactones and ketones) and chlorinated products are formed. Above pH 8, one oxidation product, 3,4-dimethoxyacetophenone, predominates. No chlorinated products are found at a high pH. The mechanisms of formation of all these products are discussed. Acta Chemica Scandinavica 1996.

Facile Synthesis of Chloro-substituted Aromatic Ethers by Use of Benzyltrimethylammonium Tetrachloroiodate

The reaction of aromatic ethers with a calculated amount of benzyltrimethylammonium tetrachloroiodate in acetic acid (or dichloromethane) under mild conditions gave, selectively, the objective chloro-substituted aromatic ethers in good yields.