2775-86-2 Usage
General Description
2,4(1H,3H)-Pyrimidinedione, 1-benzoyl-, also known as barbituric acid, is a chemical compound commonly used as a precursor in the synthesis of other pharmaceuticals, such as barbiturates and some antineoplastic agents. It is a crystalline solid with a white to off-white color. Barbituric acid is synthesized by the reaction of urea and malonic acid in the presence of phosphorus oxychloride. It has a wide range of applications in the pharmaceutical and medicinal industries, and its derivatives have sedative, hypnotic, and anticonvulsant properties. It is important to handle barbituric acid with care and use protective equipment, as it can be harmful if ingested, inhaled, or if it comes into contact with the skin or eyes.
Check Digit Verification of cas no
The CAS Registry Mumber 2775-86-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,7,7 and 5 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 2775-86:
(6*2)+(5*7)+(4*7)+(3*5)+(2*8)+(1*6)=112
112 % 10 = 2
So 2775-86-2 is a valid CAS Registry Number.
2775-86-2Relevant articles and documents
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Chambers
, p. 219,224 (1965)
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Microwave-assisted synthesis of amides from various amines and benzoyl chloride under solvent-free conditions: A rapid and efficient method for selective protection of diverse amines
Li, Yanqiu,Wang, Yulu,Wang, Jinye
, p. 358 - 361 (2008/12/22)
A number of structurally diverse amides were synthesized by reaction of the corresponding amines with benzoyl chloride under microwave irradiation. The proposed procedure ensures short reaction time, high yields, and excellent selectivity and considerably broadens the series of amines as compared to the microwave-assisted synthesis of amides directly from carboxylic acids. It can also be used for selective protection of various amines, including aromatic, aliphatic, and heterocyclic.
AMIDOALKYLATION OF PYRIMIDINE BASES OF NUCLEIC ACIDS
Khutova, B. M.,Klyuchko, S. V.,Prikazchikova, L. P.
, p. 407 - 409 (2007/10/02)
The reaction of uracil, thymine, and cytosine with acid N-α-chloroalkylamides gave N-substituted derivatives of these compounds.Conditions for the selective amidoalkylation of pyrimidine bases in the 1 position were found.
