27772-90-3Relevant articles and documents
The glutamate receptor GluR5 agonist (S)-2-Amino-3-(3-hydroxy-7,8-dihydro- 6H-cyclohepta[d]isoxazol-4-yl)propionic acid and the 8-methyl analogue: Synthesis, molecular pharmacology, and biostructural characterization
, p. 4911 - 4922 (2009)
The design, synthesis, and pharmacological characterization of a highly potent and selective glutamate GluR5 agonist is reported. (S)-2-Amino-3-((RS)-3- hydroxy-8-methyl-7,8-dihydro-6H-cyclohepta-[d]isoxazol-4-yl)propionic acid (5) is the 8-methyl analogu