278600-51-4Relevant articles and documents
Design, synthesis, and structure - Activity relationship studies of ATP analogues as DNA gyrase inhibitors
Luebbers, Thomas,Angehrn, Peter,Gmuender, Hans,Herzig, Silvia,Kulhanek, Josef
, p. 821 - 826 (2007/10/03)
We report herein the design and synthesis of ATP-analogues, namely 4-amino-pyrazolo[3,4-d]pyrimidines and 4-amino-pyrazolo[1,5-a][1,3,5]triazines, with DNA gyrase inhibitory activity. Among these series, some compounds exhibited promising antibacterial activity. (C) 2000 Elsevier Science Ltd. All rights reserved.