28126-22-9 Usage
Chemical Structure
C10H13Cl3N2O4
Physical State
Solid
Color
White to off-white crystalline solid
Melting Point
72-75°C (161.6-167.5°F)
Boiling Point
Decomposes above 200°C (392°F)
Solubility
Slightly soluble in water, soluble in organic solvents like acetone, ethyl acetate, and methanol
Molecular Weight
256.58 g/mol
Chemical Properties
Aldicarb is stable under normal temperature and pressure but can decompose when exposed to high temperatures or direct sunlight. It is highly toxic to insects and nematodes due to its ability to inhibit acetylcholinesterase enzyme activity.
Uses
Aldicarb is used as an insecticide and nematicide in agriculture, horticulture, and household applications to control a wide range of insect pests.
Toxicity
Highly toxic to humans and non-target organisms, with potential side effects including nausea, vomiting, diarrhea, difficulty breathing, and in severe cases, death.
Environmental Concerns
Aldicarb has been banned or severely restricted in several countries due to its high toxicity and potential for environmental contamination. It can contaminate soil and water sources, and is harmful to beneficial insects and wildlife.
Check Digit Verification of cas no
The CAS Registry Mumber 28126-22-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,1,2 and 6 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 28126-22:
(7*2)+(6*8)+(5*1)+(4*2)+(3*6)+(2*2)+(1*2)=99
99 % 10 = 9
So 28126-22-9 is a valid CAS Registry Number.
28126-22-9Relevant articles and documents
Catalytic Decarboxylative C?N Formation to Generate Alkyl, Alkenyl, and Aryl Amines
Zhang, Yipin,Ge, Xia,Lu, Hongjian,Li, Guigen
supporting information, p. 1845 - 1852 (2020/12/01)
Transition-metal-catalyzed sp2 C?N bond formation is a reliable method for the synthesis of aryl amines. Catalytic sp3 C?N formation reactions have been reported occasionally, and methods that can realize both sp2 and sp3 C?N formation are relatively unexplored. Herein, we address this challenge with a method of catalytic decarboxylative C?N formation that proceeds through a cascade carboxylic acid activation, acyl azide formation, Curtius rearrangement and nucleophilic addition reaction. The reaction uses naturally abundant organic carboxylic acids as carbon sources, readily prepared azidoformates as the nitrogen sources, and 4-dimethylaminopyridine (DMAP) and Cu(OAc)2 as catalysts with as low as 0.1 mol % loading, providing protected alkyl, alkenyl and aryl amines in high yields with gaseous N2 and CO2 as the only byproducts. Examples are demonstrated of the late-stage functionalization of natural products and drug molecules, stereospecific synthesis of useful α-chiral alkyl amines, and rapid construction of different ureas and primary amines.
