28128-12-3Relevant articles and documents
Synthesis of indoles through acceptorless dehydrogenative coupling catalyzed by nickel on silica-alumina
Charvieux, Aubin,Hammoud, Abdul Aziz,Duclos, Marie-Christine,Duguet, Nicolas,Métay, Estelle
, (2021/07/25)
The high atom-economical formation of indoles from anilines and diols was described with affordable and easy to handle Ni/SiO2-Al2O3. After optimization, 2,3-dimethylindole was isolated with an excellent 98% yield in neat conditions. The scope of the reaction was studied and 13 indoles were isolated in 16–80% yields.
Pyrazine Radical Cations as a Catalyst for the Aerobic Oxidation of Amines
Brisar, Rok,Hollmann, Dirk,Mejia, Esteban
, p. 5391 - 5398 (2017/10/06)
An efficient and green synthetic method for the preparation of N,N-disubstituted tetramethylpyrazinium radical cations was developed, which does not require any solvent or strong alkylating agents. The investigation by UV/Vis and electron paramagnetic res
Heteroannulation of arynes with N-aryl-α-aminoketones for the synthesis of unsymmetrical N-aryl-2,3-disubstituted indoles: An aryne twist of Bischler-Moehlau indole synthesis
Bunescu, Ala,Piemontesi, Cyril,Wang, Qian,Zhu, Jieping
supporting information, p. 10284 - 10286 (2013/10/22)
Reaction of 2-(trimethylsilyl)aryl triflates 1 with N-aryl-α-amino ketones 2 afforded N-aryl-2,3-disubstituted indoles in good to excellent yields with complete control of the substitution patterns. This methodology allowed for the first time a one-step s
