28151-46-4

Basic information

• Product Name: Benzenemethanamine, N-(4-phenylcyclohexyl)-, trans-
• CAS NO: 28151-46-4
• Molecular Formula: C19H23N
• Molecular Weight: 265.398
• Mol File: 28151-46-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzenemethanamine, N-(4-phenylcyclohexyl)-, trans-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanamine, N-(4-phenylcyclohexyl)-, trans-(28151-46-4)
• EPA Substance Registry System: Benzenemethanamine, N-(4-phenylcyclohexyl)-, trans-(28151-46-4)

Safety Data

• Hazardous Substances Data: 28151-46-4(Hazardous Substances Data)

Upstream product

• 4894-75-1 1-phenyl-4-cyclohexanone 
• 100-46-9 benzylamine 
• 5769-10-8 trans-4-phenylcyclohexan-1-amine 
• 100-52-7 benzaldehyde 

Downstream Products

• 5769-10-8 trans-4-phenylcyclohexan-1-amine 
• 74068-62-5 2-[Benzyl-(4-phenyl-cyclohexyl)-amino]-1-(3,5-dimethoxy-phenyl)-ethanone 

Relevant articles and documents

INHIBITORS OF DIHYDROCERAMIDE DESATURASE FOR TREATING DISEASE

Disclosed herein are dihydroceramide desaturase 1 (Des1) inhibitor compounds and compositions, which are useful in the treatment of diseases, such as metabolic disorders, where inhibition of Des1 is expected to be therapeutic to a patient. Methods of inhibition of Des1 activity in a human or animal subject are also provided.

Hydride reagents for stereoselective reductive amination. An improved preparation of 3-endo-tropanamine

The reductive amination of substituted cyclohexanones with sodium triacyloxyborohydrides derived from NaBH4 and various carboxylic acids provides highly diastereoselective conversions to protected axial amines. This method was applied to the stereoselective preparation of 3-endo-tropanamine.