281655-37-6 Usage
Description
(S)-FMOC-2-CARBOXYMORPHOLINE, also known as 4-Fmoc-3(S)-morpholinecarboxylic Acid, is a white powder chemical compound that plays a significant role in the synthesis of various pharmaceutical compounds. It is a derivative of morpholine, an organic compound with a five-membered ring containing two nitrogen atoms and two methylene groups. The Fmoc (9-fluorenylmethoxycarbonyl) group is a protecting group for amino acids, which is commonly used in peptide synthesis.
Uses
Used in Pharmaceutical Industry:
(S)-FMOC-2-CARBOXYMORPHOLINE is used as a key intermediate for the synthesis of heterocyclic core analogs of a direct thrombin inhibitor. Thrombin inhibitors are essential in the development of anticoagulant drugs, which help prevent blood clot formation and are crucial in the treatment of various cardiovascular and thrombotic disorders.
Additionally, due to its unique chemical structure, (S)-FMOC-2-CARBOXYMORPHOLINE can be utilized in the development of other pharmaceutical compounds with potential applications in various therapeutic areas, such as pain management, inflammation, and central nervous system disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 281655-37-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,8,1,6,5 and 5 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 281655-37:
(8*2)+(7*8)+(6*1)+(5*6)+(4*5)+(3*5)+(2*3)+(1*7)=156
156 % 10 = 6
So 281655-37-6 is a valid CAS Registry Number.
InChI:InChI=1/C20H19NO5/c22-19(23)18-12-25-10-9-21(18)20(24)26-11-17-15-7-3-1-5-13(15)14-6-2-4-8-16(14)17/h1-8,17-18H,9-12H2,(H,22,23)/t18-/m0/s1
281655-37-6Relevant articles and documents
Compound as apoptosis protein inhibitor, and application thereof
-
, (2018/09/12)
The present invention belongs to the field of medical chemistry, relates to a class of compounds of apoptosis protein inhibitors, and applications thereof, and particularly provides a compound represented by a formula I, or an isomer thereof, a pharmaceut
THROMBIN INHIBITORS
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Page/Page column 33; 34, (2013/10/21)
Compounds of the invention are useful in inhibiting thrombin and associated thrombotic occlusions having the following structure: (I) or a pharmaceutically acceptable salt thereof, wherein Q is CH2, NR4, O, S, S(O) or S(O2
An annulation reaction for the synthesis of morpholines, thiomorpholines, and piperazines from β-heteroatom amino compounds and vinyl sulfonium salts
Yar, Muhammad,McGarrigle, Eoghan M.,Aggarwal, Varinder K.
, p. 3784 - 3786 (2008/12/23)
(Chemical Equation Presented) Heterocycling: Diphenyl vinyl sulfonium salt 1 acts first as an electrophile, then a base, and then again as an electrophile in this operationally simple, high yielding, one-pot synthesis of pharmacologically important morpholines, thiomorpholines, and piperazines. Compound 1 is an excellent synthon for the 1,2-ethane dication.
